Microwave-field-driven acoustic modes in DNA

Edwards, Glenn S.; Davis, Christophér C.; Saffer, Jeffrey D.; Swicord, Mays L.

doi:10.1016/s0006-3495(85)83984-9

Cited by 52 publications

(24 citation statements)

References 21 publications

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“…After some initial reports that frequency specific absorption in plasmids of DNA could occur [Swicord and Davis, 1982;Edwards et al, 1984Edwards et al, , 1985, follow-up investigations revealed that this was not the case [Foster et al, 1987;Gabriel et al, 1987]. This is an important observation, since without evidence of a direct and unique absorption mechanism that could result in redistribution in some manner of the absorbed energy in the molecule, the alternative is that some type of direct bond breakage was occurring.…”

Section: Direct Damage Due To Absorption Of the Rf By Dna In Solutionmentioning

confidence: 98%

Radiofrequency exposure and mammalian cell toxicity, genotoxicity, and transformation

Meltz

2003

Bioelectromagnetics

106

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The published in vitro literature relevant to the issue of the possible induction of toxicity, genotoxicity, and transformation of mammalian cells due to radiofrequency field (RF) exposure is examined. In some instances, information about related in vivo studies is presented. The review is from the perspective of technical merit and also biological consistency, especially with regard to those publications reporting a positive effect. The weight of evidence available indicates that, for a variety of frequencies and modulations with both short and long exposure times, at exposure levels that do not (or in some instances do) heat the biological sample such that there is a measurable increase in temperature, RF exposure does not induce (a) DNA strand breaks, (b) chromosome aberrations, (c) sister chromatid exchanges (SCEs), (d) DNA repair synthesis, (e) phenotypic mutation, or (f) transformation (cancer-like changes). While there is limited experimental evidence that RF exposure induces micronuclei formation, there is abundant evidence that it does not. There is some evidence that RF exposure does not induce DNA excision repair, suggesting the absence of base damage. There is also evidence that RF exposure does not inhibit excision repair after the induction of thymine dimers by UVexposure, as well as evidence that indicates that RF is not a co-carcinogen or a tumor promoter. The article is in part a tutorial, so that the reader can consider similarities and discrepancies between reports of RF-induced effects relative to one another. Bioelectromagnetics Supplement 6:S196-S213,

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Section: Direct Damage Due To Absorption Of the Rf By Dna In Solutionmentioning

confidence: 98%

Radiofrequency exposure and mammalian cell toxicity, genotoxicity, and transformation

Meltz

2003

Bioelectromagnetics

106

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“…In columns 2-4 for Li-DNA. The Brillouin frequency shift (measured in a 45' -45" scattering geometry) and the corresponding velocity for phonons propagating parallel to the helix axis are listed in columns 5 and 6 for Li-DNA.…”

Section: Phonon Velocitiesmentioning

confidence: 99%

A Brillouin scattering study of the hydration of Li‐ and Na‐DNA films

et al. 1987

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SynopsisWe have used Brillouin spectroscopy to study the velocities and attenuation of acoustic phonons in wet-spun films of Na-DNA and Li-DNA as a function of the degree of hydration at room temperature. Our data for the longitudinal acoustic (LA) phonon velocity vs water content display several interesting features and reveal effects that we can model at the atomic level as interhelical bond softening and relaxation of the hydration shell. The model for interhelical softening makes use of other physical parameters of these films, which we have determined by gravimetric, x-ray, and optical microscopy studies. We extract intrinsic elastic constants for hydrated Na-DNA molecules of cI1 = 8.0 x 10''' dynes/cmz and c,. = 5.7 x 10" dynes/cm2, which corresponds to a Young's modulus, E = 1.1 X 10'" dynes/cm' (with Poisson's ratio, CJ = 0.441. The negative velocity anisotropy of the LA phonons indicates that neighboring DNA molecules are held together by strong interhelical bonds in the solid state. The LA phonon attenuation data can be understood by the relaxational model in which the acoustic phonon is coupled to a relaxation mode of the water niolecules. Na-DNA undergoes the A to B phase transition at a relative humidity (rh) of 92% while Li-DNA (which remains in the B form in this range) decrystallizes at an rh of 84%. We find that our Brillouin results for Na-and Li-DNA are remarkably similar, indicating that the A to B phase transition does not play an important role in determining the acoustic properties of these two types of DNA.

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“…In addition, the longitudinal vibrational frequency can be affected by the length of DNA molecules, which could just be considered as a factor affecting vibration frequency. In the theoretical calculation, we choose ω D = 40 GHz and τ D = 5 ns as the vibration frequency and lifetime of DNA molecules [22,29-31]. For our study, we can safely select the decay rate of the peptide quantum dot as Γ 1 = 16 GHz for any practical purpose [32].…”

Section: Resultsmentioning

confidence: 99%

“…Therefore, in small volume of aqueous solution, the only vibration mode we care about is the longitudinal vibration mode. In addition, flexion of DNA molecules will result in extensions and compressions of the model, which will finally lead to the modification of the quantum dot levels through the longitudinal strain [21,22]. The Hamiltonian caused by the coupling of DNA molecules and a quantum dot has the form as follows: …”

Section: Methodsmentioning

confidence: 99%

Tunable optical Kerr effects of DNAs coupled to quantum dots

Zhu

2012

Nanoscale Res Lett

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The coupling between DNA molecules and quantum dots can result in impressive nonlinear optical properties. In this paper, we theoretically demonstrate the significant enhancement of Kerr coefficient of signal light using optical pump-probe technique when the pump-exciton detuning is zero, and the probe-exciton detuning is adjusted properly to the frequency of DNA vibration mode. The magnitude of optical Kerr coefficient can be tuned by modifying the intensity of the pump beam. It is shown clearly that this phenomenon cannot occur without the DNA-quantum dot coupling. The present research will lead us to know more about the anomalous nonlinear optical behaviors in the hybrid DNA-quantum dot systems, which may have potential applications in the fields such as DNA detection.

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Microwave-field-driven acoustic modes in DNA

Cited by 52 publications

References 21 publications

Radiofrequency exposure and mammalian cell toxicity, genotoxicity, and transformation

Radiofrequency exposure and mammalian cell toxicity, genotoxicity, and transformation

A Brillouin scattering study of the hydration of Li‐ and Na‐DNA films

Tunable optical Kerr effects of DNAs coupled to quantum dots

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