Microwave Activation of Enzymatic Catalysis

Young, Douglas D.; Nichols, Jason M.; Kelly, Robert M.; Deiters, Alexander

doi:10.1021/ja802404g

Cited by 103 publications

(68 citation statements)

References 24 publications

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“…As an example, these effects are used in biocatalysis discipline (Réjasse et al, 2004;2006;Yadav & Borkar, 2009;Souza et al, 2009), DNA hybridization (Edwards, Young, & Deiters, 2009) and the studies that evaluate enzyme stability with the use of microwave irradiation (Rejasse et al, 2007;Young et al, 2008;Izquierdo et al, 2007;Porcelli et al, 1997;La Cara et al, 1999). Recently, Laurence et al (2000), H. Bohr and J. Bohr (2000), Pomerai et al (2003) reported unfolding or structural changes in proteins with microwave irradiations and suggested the inclusion of www.ccsenet.org/ijc…”

Section: Applications In Proteomicsmentioning

confidence: 99%

Microwave Assisted Reactions in Organic Chemistry: A Review of Recent Advances

Jacob¹

2012

IJC

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Revolution in organic compound synthesis has been promoted by microwave assisted organic syntheses (MAOS) by which small molecules are built up into large polymers in a fraction of time. The need for different organic compound libraries for drug discovery, biomaterial development, automated library screening; proteomics etc has supported the emergence of innovative technologies for rapid combinatorial organic synthesis using MAOS synthesis. In previous reviews on this subject the focus of MAOS has been on the process of MAOS reactions rather than the importance given to the related applications. This review focuses on solid-phase synthesis, biopolymer synthesis, applications in proteomics, parallel processing in microwave reactors and automated library generation by means of sequential microwave irradiation methods. This article has discussed the different applications of Microwave assisted synthesis of organic polymeric compounds most thoroughly by focusing on aspects of speed, reproducibility and scalability. From this review it is clearly identified that independent on the type of organic material, data consistently points out to MW as a novel and powerful tool which has enable synthesis of a number of new compounds and presents the need for future research in this area.

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Section: Applications In Proteomicsmentioning

confidence: 99%

Microwave Assisted Reactions in Organic Chemistry: A Review of Recent Advances

Jacob¹

2012

IJC

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“…Microwave irradiation have been used in various processes, such as chemical reaction [19,20], material synthesis [21], nanotechnology [22] and biochemical processes [23,24]. It has been reported that microwave irradiation could raise the yield and reduced the reaction time in the synthesis of carbonates from CO 2 and epoxide [25], NaHCO 3 and olefins [26], CO and diols [27], and polycarbonates from open-ring polymerization of trimethylene carbonate [28].…”

Section: Introductionmentioning

confidence: 99%

Microwave assisted synthesis of glycerol carbonate from glycerol and urea

Zhang

et al. 2017

Pure and Applied Chemistry

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Abstract:The transformation of glycerol into value-added chemicals is an interesting topic in Green Chemistry. The glycerolysis of urea into glycerol carbonate is an important route of glycerol transformation. In this work, the synthesis of glycerol carbonate from glycerol and urea was performed under microwave irradiation and solvent free conditions. The catalytic properties of ZnSO 4 , ZnCl 2 , CuSO 4 and MgSO 4 were tested and ZnSO 4 showed the best performance. The effects of catalyst amount, temperature, reaction time, microwave power, molar ratio of urea to glycerol on the reaction were studied using ZnSO 4 as the catalyst. It was demonstrated that microwave irradiation could promote the reaction effectively, and the yield of desired product glycerol carbonate could reach 93.7 %.

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“…Microwave irradiation results in an instantaneous localized superheating which is achieved due to dipole rotation or ionic conduction. Microwave irradiation has been applied to the synthesis of several natural products as well as peptides, peptoids and carbohydrates [5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

The Microwave-assisted Lipase-catalyzed Synthesis of Sucrose Laurate

Li¹,

Xin²,

Yao³

et al. 2016

Advances in Computer Science Research

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Abstract. In this study, the lauroyl sucrose ester was synthesized by microwave-assisted lipase-catalyzed reaction under non-aqueous system. The influence of the microwave power, the amount of molecular sieve added and the reaction time on the conversion of sugar esters were explored. The results showed that compared with conventional heating, microwave-assisted lipase-catalyzed method was short time and can reduce energy consumption. And the thin layer chromatography showed that the lauroyl sucrose ester synthesized by microwave-assisted lipase-catalyzed reaction containing only a single product spot. The optimal conditions was built when the reaction was carried out under 200W of the microwave reaction power and 15 g/L of molecular sieve for 25 min. The maximum conversion of lauroyl sucrose ester was 63.8% under the optimal condition.After three times batch reaction, the residual activity of lipase was 52.4%.

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Microwave Activation of Enzymatic Catalysis

Cited by 103 publications

References 24 publications

Microwave Assisted Reactions in Organic Chemistry: A Review of Recent Advances

Microwave Assisted Reactions in Organic Chemistry: A Review of Recent Advances

Microwave assisted synthesis of glycerol carbonate from glycerol and urea

The Microwave-assisted Lipase-catalyzed Synthesis of Sucrose Laurate

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