Microvascular free tissue transfer in the management of squamous cell carcinoma of the tongue during pregnancy

Squamous Cell Carcinoma of the Tongue During Pregnancy: A Case Report and Review of the Literature

“…Altered hepatic and renal pharmacokinetics additionally have consequences for possible treatments. 5,6,7,8 Conversely, the effect the malignancy has on the pregnancy must also be considered as both conditions place extra nutritional demands on the patient. Tongue cancer by its nature can also affect the ability to take in nutrition secondary to pain and dysphagia.…”

“…We identified thirty two cases of pregnant patients with tongue SCC following a literature search as shown in table 1, with the current patient included. 4,5,6,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26 We excluded cases reported as a regional recurrence of tongue SCC during pregnancy. Only one pregnant patient with SCC of the tongue in the published literature chose termination of pregnancy prior to treatment of the malignancy; however, publication bias must be considered when interpreting this.…”

Systemic lupus erythematosus, pregnancy and carcinoma of the tongue

“…From the limited literature available (5 case reports involving 7 patients in total) the majority of patients (5 cases) were successfully treated by surgery alone (resection and reconstruction) with delivery of a healthy baby 1 18–20. In one case, a limited resection was undertaken in order to avoid stress to the fetus; this patient unfortunately died from recurrence 20.…”

“…Although rare, oral cancer has been described in pregnancy 1. Surgical resection of the primary lesion with neck dissection, and reconstruction with microvascular free-tissue transfer is now the preferred treatment for patients with squamous cell carcinoma of the tongue.…”

Advanced Oral Tongue Cancer in a 22-Year-Old Pregnant Woman

“…5 Some authors theorize that the physiologic changes of pregnancy can promote neoplastic growth secondary to the high metabolic state and hormonal responses. There are 6 previous published accounts in the English language in regard to treatment of oral cancer among pregnant women (Table 1 [6][7][8][9][10][11] ).…”