Advanced Oral Tongue Cancer in a 22-Year-Old Pregnant Woman

Cheung, Esther J.; Wagner, Henry; Botti, John J.; Fedok, Fred G.; Goldenberg, David

doi:10.1177/000348940911800104

Cited by 19 publications

(9 citation statements)

References 27 publications

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“…We identified thirty two cases of pregnant patients with tongue SCC following a literature search as shown in table 1, with the current patient included. 4,5,6,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26 We excluded cases reported as a regional recurrence of tongue SCC during pregnancy. Only one pregnant patient with SCC of the tongue in the published literature chose termination of pregnancy prior to treatment of the malignancy; however, publication bias must be considered when interpreting this.…”

Section: Discussionmentioning

confidence: 99%

Squamous Cell Carcinoma of the Tongue During Pregnancy: A Case Report and Review of the Literature

Murphy

Berman

Edwards

et al. 2016

Journal of Oral and Maxillofacial Surgery

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Section: Discussionmentioning

confidence: 99%

Squamous Cell Carcinoma of the Tongue During Pregnancy: A Case Report and Review of the Literature

Murphy

Berman

Edwards

et al. 2016

Journal of Oral and Maxillofacial Surgery

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“…The etiology and pathogenesis of oral cavity cancer in young female patients could be different from those occurring in older patients (3,5). Pregnancy has been shown to be associated with OSCC but there is a paucity of data regarding this etiology as these studies are primarily case reports discussing the challenges that clinicians face in administering treatment that is of maximal benefit to the patient and minimal risk to the fetus (4,6-10). …”

Section: Introductionmentioning

confidence: 99%

Estrogen and Progesterone hormone receptor expression in oral cavity cancer

Grimm

Biegner²,

Teriete³

et al. 2016

Med Oral

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BackgroundRecent studies have shown an increase in the incidence of oral squamous cell carcinoma (OSCC) in younger patients. The hypothesis that tumors could be hormonally induced during pregnancy or in young female patients without the well-known risk factors alcohol or tobacco abuse seems to be plausible.Material and MethodsEstrogen Receptor alpha (ERα) and Progesterone Receptor (PR) expression were analyzed in normal oral mucosa (n=5), oral precursor lesions (simple hyperplasia, n=11; squamous intraepithelial neoplasia, SIN I-III, n=35), and OSCC specimen. OSCCs were stratified in a young female (n=7) study cohort and older patients (n=46). In the young female study cohort three patients (n=3/7) developed OSCC during or shortly after pregnancy. Breast cancer tissues were used as positive control for ERα and PR expression.ResultsERα expression was found in four oral precursor lesions (squamous intraepithelial neoplasia, SIN I-III, n=4/35, 11%) and in five OSCC specimen (n=5/46, 11%). The five ERα positive OSCC samples were older male patients. All patients within the young female study cohort were negatively stained for both ERα and PR.ConclusionsER expression could be regarded as a seldom risk factor for OSCC. PR expression seems to be not relevant for the development of OSCC. Key words:Oral squamous cell carcinoma, estrogen receptor, progesterone receptor, hormone receptor.

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“…2 Historically, scientific literature has demonstrated a preferential incidence of oral cancers in men aged 50 to 70 years. [2][3][4][5][6][7] However, recent epidemiological studies have shown an increase in the development of OSCC in patients under 45 years old. 8,9 In those cases, tumour behaviour is different and patients have a poor prognosis in comparison to cancer in older adults.…”

Section: Case Reportmentioning

confidence: 99%

Unusual Presentation of Oral Squamous Cell Carcinoma in a Young Woman = عرض غير عادي لسرطان الخلايا الحرشفية في الفم عند إمرأة شابة

França

Monti

Castro

et al. 2012

SQUMJ

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Oral squamous cell carcinoma (OSCC) is the most common oral malignant neoplasm, mainly affecting individuals over 50 years old with a history of tobacco and alcohol use. The occurrence of this oral cancer in individuals under 40 years old is unusual and, when it does occur, shows a weaker relation to those risk factors and a more aggressive clinical course. Due to the paucity of reports in this population, it is difficult to prove its increasing trend. A case of oral squamous cell carcinoma in a 39-year-old woman with no history of tobacco or alcohol use is reported. Clinical and histopathological findings, aetiology, and treatment are discussed. The increasing trend of oral squamous cell carcinoma in young women without known risk factors highlights the need for clinicians to be prepared to diagnose this lesion quickly and precisely, providing a better prognosis, chance of survival, and quality of life for the patient.

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Advanced Oral Tongue Cancer in a 22-Year-Old Pregnant Woman

Cited by 19 publications

References 27 publications

Squamous Cell Carcinoma of the Tongue During Pregnancy: A Case Report and Review of the Literature

Squamous Cell Carcinoma of the Tongue During Pregnancy: A Case Report and Review of the Literature

Estrogen and Progesterone hormone receptor expression in oral cavity cancer

Unusual Presentation of Oral Squamous Cell Carcinoma in a Young Woman = عرض غير عادي لسرطان الخلايا الحرشفية في الفم عند إمرأة شابة

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