Microstructure, mechanical and corrosion properties and biocompatibility of Mg–Zn–Mn alloys for biomedical application

Porous magnesium-based scaffolds for tissue engineering

“…Incorporating Zn element in contents of less than 3% can improve the corrosion resistance [60] and the mechanical properties of magnesium scaffolds [56,61].…”

Effects of Nd on the Microstructures, Mechanical Properties and in Vitro Corrosion Behavior of Cast Mg-1Mn-2Zn-<i>x</i>Nd Alloys

“…Although 2% Zn can fully dissolve in Mg matrix by the MgZn binary phase diagram, 25) the solubility of Zn in Mg decreases and the compound may produce when the other alloying elements are added. This is related to the formation of compound Mg 7 Zn 3 in the Mg-1Mn-2Zn, Mg-1Mn-3Zn alloys, 11) and Mg-1Mn-2Zn-xNd alloys in this study. The peak values of Mg 7 Zn 3 slightly increase with addition of Nd content, suggesting the increase of volume fraction of Mg 7 Zn 3 with Nd content.…”

“…As compared with the cast Mg-1Mn-2Zn alloy, 11) Cast-1 and Cast-2 exhibit slightly higher strength, but Cast-3 exhibits lower strength. This indicates that Nd is not an effective element to increase the strength of cast Mg-Mn-Zn alloys.…”

“…9) The extruded Mg-Zn alloy 10) and Mg-Mn-Zn alloys 11) exhibit great potential for biomedical applications due to their much better strength and corrosion resistance than pure Mg. However, the bending strength of extruded Mg-Zn alloy 10) decreases rapidly at the initial corrosion stage from 625 MPa to 390 MPa with about 6% loss of weight during degradation, implying the inadequate strength and/or corrosion resistance of those degradable alloys since bio-Mg alloys should possess certain mechanical and biodegradable properties to serve as suitable stent materials (specifically in cardiovascular applications): (i) appropriate mechanical characteristics at body temperature, such as sufficient ductility (a uniform strain optimally > 15%) and reasonable strength (ultimate tensile strength (UTS) > 250 MPa; (ii) a moderate and homogeneous degradation performance (biodegradable period of 1224 months); (iii) good biocompatibility.…”

Characterization of Ternary Mg-Sn-Mn Alloys

“…A study made by Zhao showed that tin addition up to 3 wt% did not cause any toxicity in Mg63 cells and improved the mechanical properties drastically [17]. Manganese addition into the magnesium alloys does not affect the tensile strength but improves the yield strength slightly, however the most important function of manganese addition is to increase resistance of the Mg alloys in salt water by forming harmless intermetallic compounds with impurities [18]. A study made by Xu showed that manganese addition into magnesium did not cause any toxicity in human body [19].…”