Microstructural organization of the pancreas of a domestic pig

Abstract

The mammalian pancreas is a gland of a mixed type of secretion. Its composition morphologically distinguishes two parts that perform different functions – exocrine and endocrine. In many diseases, there are pronounced disturbances in their work, which has a significant impact on the state of the body. Literature data concerning the microscopic organization of pancreatic tissues do not allow us to recreate a complete picture of its architectonics. The latter is necessary for understanding the physiological processes occurring in the body of animals and predicting the outcome of diseases associated with the defeat of this organ. Considering the above, we set a goal – to establish the features of the microstructural organization of the pancreas in a domestic pig. Pancreatic tissue samples obtained from five sexually mature meat-fed pigs at the age of eight months, during slaughter, were used for the research. The selected material was subjected to fixation in a 10.0% solution of neutral formalin during the day. Further processing of the selected samples in order to obtain histological sections of tissues was carried out according to generally accepted methods. based on histomorphological studies, it was found that the pancreas of a domestic pig by the type of its structure belongs to parenchymal organs, and by the type of its structural organization to complex alveolar-tubular glands. Two closely interacting parts were found in its composition. The first of them – exocrine – is represented by pancreatic acinuses and a system of excretory ducts. The second is endocrine – pancreatic islets (islets of Langerhans). At the same time, the exocrine part occupies a larger volume of the parenchyma of the organ, in comparison with the endocrine. Both of the above parts have clear morphological differences.

Basal pancreatic secretion in a comparative aspect in poultry and rodents

“…The mammalian pancreas is a gland of mixed type of secretion. It morphologically consists of two parts with different functions-exocrine and endocrine (Barteneva et al, 2022). In addition to birds, in rodents (rabbits and rats), under prolonged maintenance of a certain dietary intake, the secretory process in the pancreas undergoes adaptive changes, such as the pronounced basal secretion of electrolytes by the pancreas and its weak response to secretin (Aksyonova et al, 2021).…”