Microstructural Development of Natural Hydroxyapatite Originated from Fish‐Bone Waste through Heat Treatment

Ozawa, Masakuni; Suzuki, Suguru

doi:10.1111/j.1151-2916.2002.tb00268.x

Cited by 162 publications

(94 citation statements)

References 8 publications

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“…Extraction of HAp from the bio-wastes is a biologically safe (no foreign chemicals are utilized) and economically desirable process especially with the increasing world demand of HAp bioceramics. Many bio-wastes have been exploited for such purpose, for instance fish bones [24], bovine bones [25] and bones and teeth of pig [26]. Unfortunately, it was reported that most of the carbonate groups present in the carbonated hydroxyapatite are eliminated by heating which affects the biological properties of the obtained apatite extracted by the thermal process [22,27].…”

Section: Introductionmentioning

confidence: 99%

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Physiochemical characterizations of hydroxyapatite extracted from bovine bones by three different methods: Extraction of biologically desirable HAp

Barakat

Khalil

Sheikh

et al. 2008

Materials Science and Engineering: C

168

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Section: Introductionmentioning

confidence: 99%

“…Hence, the PLPW has been utilized to pluck the collagen and other organic compounds out the bovine bones leaving the desired natural apatite. The third process utilized in this study is direct heating of the bovine bone to remove the organic compounds which can be thermally eliminated [24][25][26]36].…”

Section: Introductionmentioning

confidence: 99%

Physiochemical characterizations of hydroxyapatite extracted from bovine bones by three different methods: Extraction of biologically desirable HAp

Barakat

Khalil

Sheikh

et al. 2008

Materials Science and Engineering: C

168

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“…Bioceramics derived from natural sources like coral [1], fish bone [2], oyster shell [3] and bovine bone, etc. [4,5] inherit some of the properties of the raw materials such as pore structure, carbonate content and minor concentration of trace elements etc.…”

Section: Introductionmentioning

confidence: 99%

Self Setting Bone Cement Formulations Based on Egg shell Derived TetraCalcium Phosphate BioCeramics

phosphate¹,

shells²,

cements³

et al. 2015

Bioceram Dev Appl

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Egg shells have been used as a calcium source for synthesis of tetra calcium phosphate (ETTCP) by solid state reaction method. The cell parameters and cell volume of ETTCP measured by X-ray powder diffraction method were lower than the tetra calcium phosphate prepared using synthetic Ca(CO) 3 (pure TTCP) for comparison. The vibration bands of ETTCP were also slightly different from the vibration bands of pure TTCP characterized by Fourier transformed infrared spectroscopy. ETTCP has been tried as a main component in a self setting bone cement to evaluate the advantages of the presence of the biologically relevant ions such as Mg 2+ , Sr 2+ , SiO 2-4 , F -, K + and Na + ions in the cement properties. The setting time of the ETTCP derived cement was ~ 11 min compared to ~ 16 min of the pure TTCP derived cement. The amount of hydroxyapatite formed as the end product was about 12% higher for ETTCP derived cement than pure TTCP derived cement after 28 days of immersion in phosphate buffer solution as confirmed by phase analysis. Elemental analysis also indicates the presence of trace elements in minor concentration in ETTCP derived cement. Although both the cements showed similar compressive strength after 28 days, the initial strength of the ETTCP derived cement was remarkably higher during initial stages of the hardening reaction (24 h-7 days) compared to TTCP derived cement. Cell viability of L6 cells was higher and cell spreading was more for the ETTCP derived cement than pure TTCP derived cement. The present study has demonstrated the advantages of eggshell derived TTCP in bone cement formulations due to the presence of biologically relevant ions. This may help the clinician with brief surgical procedure by using faster setting cement as well as the patient to have quick recovery with a higher initial strength of cement.

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“…porcine bone (Im, Chung, Lim, Choung, & Hong, 2007;Janus, Faryna, Haberko, Rakowska, & Panz, 2008;Sobczak et al, 2009), bovine bone (Barakat et al, 2008;Mezahi et al, 2009;Sobczak et al, 2009;Taniguchi et al, 1999;Tsai et al, 2010;Ueno et al, 1983), chicken bone (Kim, Rey, & Glimcher, 1996), and fish bone and scales (Mondal, Mondal, Dey, & Mukhopadhyay, 2012;Ozawa & Suzuki, 2002). In addition, it was reported that the characteristics of HA derived from biowastes could be altered by various conditions, such as the types of osseous tissue (i.e.…”

Section: Introductionmentioning

confidence: 99%

Development and Characterization of Horse Bone-derived Natural Calcium Phosphate Powders

Jang¹,

Cho²,

Seonwoo³

et al. 2014

Journal of Biosystems Engineering

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Purpose: This study was to develop an effective process for fabricating biocompatible calcium phosphate powders (CPPs) using horse bones, and to investigate the characteristics of them. Methods: The characteristics of horse bone powders (HBPs) were investigated according to the different osseous tissue types (compact bone and cancellous bone), bone types (spine and tibia), pretreatment methods (cold water, H2O2, and hot water), sintering time (4, 8 and 12h), and sintering temperature (600, 900, 1100 and1300°C). In addition, the grinding methods were compared based on the wet grinding (ball mill) and dry grinding (blade grinder) method to make it as powders. Finally, their cytotoxicity and cell viability were checked. Results: Regardless of the types of osseous tissues and bones, HBPs were well fabricated as biocompatible CPPs. It was also found that the pretreatment methods did not influence on the resultants, showing well-fabricated HBPs. Considering the processing time, the hot water method was the most suitable compared to other pretreatment methods. Further, 12h-sintering time was sufficient to remove residual organic compounds. The sintering temperatures greatly affected the properties of bone powders fabricated. The x-ray diffraction (XRD) peak of horse bone sintered at 600°C was most closed to that of hydroxyapatite (HA). Our bioactivity study demonstrated that the HBPs fabricated by sintering horse bones at 1300°C showed the best performance in terms of cell viability whereas the HBPs 1100°C showed the cytotoxicity. Conclusions: Using various types of horse bone tissues, biocompatible CPPs were successfully developed. We conclude that the HBPs may have a great potential as biomaterials for various biological applications including bone tissue engineering.

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Microstructural Development of Natural Hydroxyapatite Originated from Fish‐Bone Waste through Heat Treatment

Cited by 162 publications

References 8 publications

Physiochemical characterizations of hydroxyapatite extracted from bovine bones by three different methods: Extraction of biologically desirable HAp

Physiochemical characterizations of hydroxyapatite extracted from bovine bones by three different methods: Extraction of biologically desirable HAp

Self Setting Bone Cement Formulations Based on Egg shell Derived TetraCalcium Phosphate BioCeramics

Development and Characterization of Horse Bone-derived Natural Calcium Phosphate Powders

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