Microscopy lights up stem cells in action

Restored interlaced volumetric imaging increases image quality and scanning speed during intravital imaging in living mice

“…This approach allows for visualization within thicker specimens than was previously possible with confocal microscopy [5]. A challenge that remains to be addressed by 2-PE microscopy, however, is the imaging of cell dynamics within soft tissues in live animals-dynamic intravital imaging [6][7][8]. Dynamic intravital imaging has the potential to significantly improve our understanding of how cellular processes function in vivo.…”