“…Chen et al [121] study cancer cell motility focusing the ways to optimize the spatial search strategies, Zhang et al [127,128] propose a multi-scale tumor modeling platform that understands brain cancer, As concerning the basic structure and ingredients of a standard agent-based model built into the field of biology and medicine [110,111,125,129,130], the diverse types of agents, their behaviors (mechanisms of interaction), and their environment should be distinguished [103,131]. All these aspects are discussed in the next section with reference to our model that, placing at a quite abstract level of simulation, models the interactions of a population of tumor cells with a population of peptides and other regulatory molecules, like micro-RNA.…”