Interplay of master regulatory proteins and mRNA in gene expression: 3D Monte Carlo simulations

Bifurcations in the interplay of messenger RNA, protein and nonprotein coding RNA

“…Due to this feedback between mRNA formation and protein synthesis, the kinetics of mRNA and protein formation may be complex even in the simplest genetic networks. The corresponding models focused on bistability and oscillations in simple genetic networks and on complex networks are numerous (see recent reviews [2][3][4][5], articles [6][7][8][9][10][11][12][13][14][15][16][17], and references therein).…”