Microscopic haematuria: urological investigation using a standard protocol

Sultana, Stefan; Goodman, Carol; Byrne, D. J.; Baxby, K.

doi:10.1046/j.1464-410x.1996.01975.x

Cited by 64 publications

(41 citation statements)

References 8 publications

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“…Sultana et al showed in a study in UK that no malignancy was found in those < 50 years old who presented with microscopic haematuria when compared to 7.5% in those > 50 years of age (Sultana and Baxby, 1996). The authors argued that the investigations of older patients with microscopic haematuria (and all those with frank haematuria) is well justified, as malignancy will be found in a significant proportion even if they are asymptomatic.…”

Section: 2515 Assessment and Clinical Significance Of Haematuria In mentioning

confidence: 99%

Assessment and Clinical Significance of Haematuria in Malaysian Patients - Relevance to Early Cancer Diagnosis

Ng¹,

Htun²,

Dublin³

et al. 2012

Asian Pacific Journal of Cancer Prevention

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Section: 2515 Assessment and Clinical Significance Of Haematuria In mentioning

confidence: 99%

Assessment and Clinical Significance of Haematuria in Malaysian Patients - Relevance to Early Cancer Diagnosis

Ng¹,

Htun²,

Dublin³

et al. 2012

Asian Pacific Journal of Cancer Prevention

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“…Typically, the majority of patients with bladder cancer present with gross painless hematuria, with estimates of this presentation accounting for up to 85% of patients at initial diagnosis (3,4). Asymptomatic microhematuria is the next most common presenting symptom for bladder cancer with up to 10% of patients evaluated for the presence of microscopic hematuria being diagnosed with bladder cancer (5). The remaining small subset of newly diagnosed bladder cancer patients will present with symptoms that mimic other common urological conditions, such as urinary tract infections and/or lower urinary tract symptoms (LUTS).…”

Section: Introductionmentioning

confidence: 99%

Incidence and clinical characteristics of lower urinary tract symptoms as a presenting symptom for patients with newly diagnosed bladder cancer

et al. 2014

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ARTICLE INFO ______________________________________________________________ ______________________Purpose: The incidence of lower urinary tract symptoms (LUTS) as the sole presenting symptom for bladder cancer has traditionally been reported to be low. The objective of this study was to evaluate the prevalence and clinical characteristics of newly diagnosed bladder cancer patients who presented with LUTS in the absence of gross or microscopic hematuria. Materials and Methods:We queried our database of bladder cancer patients at the Atlanta Veteran's Affairs Medical Center (AVAMC) to identify patients who presented solely with LUTS and were subsequently diagnosed with bladder cancer. Demographic, clinical, and pathologic variables were examined. Results: 4.1% (14/340) of bladder cancer patients in our series presented solely with LUTS. Mean age and Charlson Co-morbidity Index of these patients was 66.4 years (range = 52-83) and 3 (range = 0-7), respectively. Of the 14 patients in our cohort presenting with LUTS, 9 (64.3%), 4 (28.6%), and 1 (7.1%) patients presented with clinical stage Ta, carcinoma in Situ (CIS), and T2 disease. At a median follow-up of 3.79 years, recurrence occurred in 7 (50.0%) patients with progression occurring in 1 (7.1%) patient. 11 (78.6%) patients were alive and currently disease free, and 3 (21.4%) patients had died, with only one (7.1%) death attributable to bladder cancer. Conclusions: Our database shows a 4.1% incidence of LUTS as the sole presenting symptom in patients with newly diagnosed bladder cancer. This study suggests that urologists should have a low threshold for evaluating patients with unexplained LUTS for underlying bladder cancer.

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“…Das MD-KOVA®-System ist eine Weiterentwicklung des Zählkammerverfah-rens und lässt eine qualitativ und quantitativ sicherere Beurteilung des Urinsediments zu. [12,13], wohingegen bei gemischten Kollektiven die Rate auf 13% ansteigt [14]. Wenn eine Makrohämaturie vorliegt, steigt die Wahrscheinlichkeit in einem Kollektiv >40 Jahre alter Patienten auf etwa 40% [15].…”

Section: Nachweisverfahrenunclassified

Methodik und aktueller Stellenwert der Mikrohämaturiediagnostik

Hüppe

Wawroschek

2011

Urologe

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Haematuria is the main symptom of malignant diseases of the urinary tract. Hence urine analysis for the detection of microscopic haematuria is an accepted diagnostic procedure in daily urologic practice. Until now there are neither international nor national agreements relating to the definition of microscopic haematuria, the choice of verification procedures and a diagnostic algorithm. As there are diverse reasons for microscopic haematuria the extent of continuative diagnostics should be adapted to the existence of risk factors for a clinically apparent disease. Low-risk patients with asymptomatic microscopic haematuria do not necessarily have to undergo primary cystoscopy if there are no pathological findings on urine cytology or ultrasound examination. Microhaematuria in high-risk patients should lead to a more intensive evaluation of the urinary tract, which should include cystoscopy and imaging of the upper urinary tract. In the diagnostics of microhaematuria you have to be aware of that intermittent bleeding is often characteristic of urothelial malignancies. Therefore, a single negative urine analysis should not lead to abandonment of further diagnostic procedures.

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Microscopic haematuria: urological investigation using a standard protocol

Cited by 64 publications

References 8 publications

Assessment and Clinical Significance of Haematuria in Malaysian Patients - Relevance to Early Cancer Diagnosis

Assessment and Clinical Significance of Haematuria in Malaysian Patients - Relevance to Early Cancer Diagnosis

Incidence and clinical characteristics of lower urinary tract symptoms as a presenting symptom for patients with newly diagnosed bladder cancer

Methodik und aktueller Stellenwert der Mikrohämaturiediagnostik

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