“…Recent advances in sequencing technologies have made it possible to systematically identify critical genetic and epigenetic alterations in various types of melanoma. Additionally, the availability of bulk transcriptome information from cancer genome databases has enabled the mining and translating data from multiple genomics aspects [ 18 , 19 ]. In this study, we leverage several landmark datasets to construct an immune-based prognostic signature through an extensive network analysis of immune-related gene profiles in SKCM.…”