We report on room temperature operation of green electron beam pumped semiconductor lasers based on multiple ZnSe quantum wells with CdSe quantum disk sheets, embedded in the ZnSSe/ZnSe alternatelystrained superlattice waveguide. An efficiency of 4% per facet at electron beam energies of 18-21 keV was achieved. The output pulse power up to 12 W was detected.Electron-beam-pumped (EBP) green semiconductor lasers based on ZnSe can be successfully used for numerous applications, such as projection television, optical communications via plastic fibers, medicine etc. The method of electron-beam excitation [1] has some specific features. First, the EBP lasers do not need in a p-n junction and contacts. Therefore, they are out of doping problems, especially the p-type ones inherent for all wide gap materials, like ZnSe. Since the electrical and optical instability of N-acceptors has been shown to be responsible for the slow degradation of ZnSe green laser diodes [2,3], one can expect the strongly enhanced degradation stability of undoped ZnSe-based EBP lasers. In addition, they have no problems of carrier transport from n-and p-type cladding layers to a laser active region. Due to the bulk nature of the electron-beam excitation the thickness of an active region of EBP lasers can be significantly larger than that of injection pumped lasers, the latter being limited by a thickness of the space charge region at a pn junction. Using of thick active region allows one to obtain the higher level of output power in EBP lasers in comparison with injection lasers. By increasing the electron beam cross-section, one can pump the laser arrays consisted of a number of single lasers, which enables one either to increase further the output power or demonstrate lasing at multiple wavelengths simultaneously.However, the application of such lasers is strongly restricted by both a relatively high threshold current density at room-temperature (RT) and a high energy of the electron beam needed for laser generation. Sufficient progress in the development of EBP lasers has been achieved using semiconductor heterostructures as the laser active elements instead of bulk materials. The lasing with microgun excitation both in infrared at RT and in blue-green spectral region at cryogenic temperatures have been demonstrated [4,5]. Fabrication of EBP blue-green RT lasers based on alternately-strained superlattice waveguide with the value of threshold current density as low as 0.8 A/cm2 and pulse output power as high as 9 W has been recently reported [6,7]. The value of external quantum efficiency of 1.6% per facet has been registered [6]. This paper report on modification of the active region of Cd(Zn)Se-based green RT EBP lasers, resulting in the efficiency as high as 4% per one facet at the electron beam energy of 18-21 keV.