Microfluidic Synthesis of Functional Nanoparticles

Han, Zhaobin; Jiang, Xingyu

doi:10.1002/9783527818341.ch10

Cited by 17 publications

(12 citation statements)

References 102 publications

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“…Furthermore, microfluidic chips are highly integrated and can achieve adequate mixing of reagents before performing the reaction according to the reaction conditions. [36][37][38][39] Nanoparticle preparation by microreactors can be divided into three main categories: continuous laminar flow, segmented flow, and droplet-based microreactors. [40][41][42] The continuous laminar flow microreactor is currently the most common and it is relatively the simplest in design and operation.…”

Section: Synthesis Of Nanoparticles By Microfluidic Technologymentioning

confidence: 99%

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Intelligent control of nanoparticle synthesis through machine learning

Chen

2022

Nanoscale

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Section: Synthesis Of Nanoparticles By Microfluidic Technologymentioning

confidence: 99%

“…Furthermore, microfluidic chips are highly integrated and can achieve adequate mixing of reagents before performing the reaction according to the reaction conditions. 36–39…”

Section: Synthesis Of Nanoparticles By Microfluidic Technologymentioning

confidence: 99%

Intelligent control of nanoparticle synthesis through machine learning

Chen

2022

Nanoscale

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“…The segmented flow pattern showed maximum mixing in the channel, further phase separation interfaces provided a high site for the reaction. Due to higher agitation and well-mixed condition in segmented flow microreactors they produce nanoparticles with narrow size [ 75 ]. Khan et al [ 36 ] attempted to develop the shell coating without the second nucleation by manipulating reactions in a multistage microfluidic system.…”

Section: Nanoparticles Synthesis Using Microreactorsmentioning

confidence: 99%

Process Intensification Approach Using Microreactors for Synthesizing Nanomaterials—A Critical Review

et al. 2021

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Nanomaterials have found many applications due to their unique properties such as high surface-to-volume ratio, density, strength, and many more. This review focuses on the recent developments on the synthesis of nanomaterials using process intensification. The review covers the designing of microreactors, design principles, and fundamental mechanisms involved in process intensification using microreactors for synthesizing nanomaterials. The microfluidics technology operates in continuous mode as well as the segmented flow of gas–liquid combinations. Various examples from the literature are discussed in detail highlighting the advantages and disadvantages of microfluidics technology for nanomaterial synthesis.

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“…Resulting in the following advantages: sufficient mixing in millisecond range and improved (rapid) heat and mass transfer. Additionally, the procedures offer other advantages such as flexible design and fabrication, fast change and screening of reaction parameters, cost efficiency, improved product quality, high throughput, higher reproducibility and the feasibility of automating the entire production process, including purification [27,65,66]. In contrast to conventional synthetic routes, continuous flow microreactors provide the separation of the two major steps during the formation of MNPs; (i) a rapid nucleation of the NP seeds occurs inside the microreactor, while the (ii) comparatively slow growth of NP takes place in the connected capillary, or ripening zone.…”

Section: Microfluidic Synthesismentioning

confidence: 99%

Advances in Magnetic Nanoparticles Engineering for Biomedical Applications—A Review

2021

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Magnetic iron oxide nanoparticles (MNPs) have been developed and applied for a broad range of biomedical applications, such as diagnostic imaging, magnetic fluid hyperthermia, targeted drug delivery, gene therapy and tissue repair. As one key element, reproducible synthesis routes of MNPs are capable of controlling and adjusting structure, size, shape and magnetic properties are mandatory. In this review, we discuss advanced methods for engineering and utilizing MNPs, such as continuous synthesis approaches using microtechnologies and the biosynthesis of magnetosomes, biotechnological synthesized iron oxide nanoparticles from bacteria. We compare the technologies and resulting MNPs with conventional synthetic routes. Prominent biomedical applications of the MNPs such as diagnostic imaging, magnetic fluid hyperthermia, targeted drug delivery and magnetic actuation in micro/nanorobots will be presented.

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Microfluidic Synthesis of Functional Nanoparticles

Cited by 17 publications

References 102 publications

Intelligent control of nanoparticle synthesis through machine learning

Intelligent control of nanoparticle synthesis through machine learning

Process Intensification Approach Using Microreactors for Synthesizing Nanomaterials—A Critical Review

Advances in Magnetic Nanoparticles Engineering for Biomedical Applications—A Review

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