Microfluidic fabrication of fluorescent nanomaterials: A review

Lin, Liangliang; Yin, Yufeng; Starostin, Sergey A.; Xu, Huifang; Li, Chengdong; Wu, Ke‐Jun; He, Chao‐Hong; Hessel, Volker

doi:10.1016/j.cej.2021.131511

Cited by 39 publications

(23 citation statements)

References 139 publications

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“…The work in [ 171 ] showed that the flexible laminated graphene paper electrode was an economical and efficient alternative to glassy carbon and platinum-wire electrodes and showed that the performance of the flexible laminated graphene paper, K + selective solid-contact ISE, was comparable to the most advanced solid-contact ISE. Microfluidics, characterized by fluid manipulation in submillimeter channels/reactors, are of great concern in many areas such as polymer synthesis, fine chemical processing, and biomedicine [ 172 , 173 , 174 ]. The study in [ 175 ] introduced a new concept of solid reference electrodes integrated with microfluidic paper-based sampling and was successfully used for ion determination in environmental and clinically relevant samples.…”

Section: Prospection Of Crop Detection Applicationsmentioning

confidence: 99%

Unlocking All-Solid Ion Selective Electrodes: Prospects in Crop Detection

Zhai

Luo

et al. 2022

Sensors

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This paper reviews the development of all-solid-state ion-selective electrodes (ASSISEs) for agricultural crop detection. Both nutrient ions and heavy metal ions inside and outside the plant have a significant influence on crop growth. This review begins with the detection principle of ASSISEs. The second section introduces the key characteristics of ASSISE and demonstrates its feasibility in crop detection based on previous research. The third section considers the development of ASSISEs in the detection of corps internally and externally (e.g., crop nutrition, heavy metal pollution, soil salinization, N enrichment, and sensor miniaturization, etc.) and discusses the interference of the test environment. The suggestions and conclusions discussed in this paper may provide the foundation for additional research into ion detection for crops.

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Section: Prospection Of Crop Detection Applicationsmentioning

confidence: 99%

Unlocking All-Solid Ion Selective Electrodes: Prospects in Crop Detection

Zhai

Luo

et al. 2022

Sensors

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“…Moreover, it can reduce photobleaching of the encapsulated dye and increase the biocompatibility of the fluorescently labeled system in case the fluorescent dye is toxic . Particles with good optical properties have been widely used in bioimaging, labeling, and sensing …”

Section: Introductionmentioning

confidence: 99%

Four-Level Structural Hierarchy: Microfluidically Supported Synthesis of Polymer Particle Architectures Incorporating Fluorescence-Labeled Components and Metal Nanoparticles

Mazetyte‐Stasinskiene

Freiberger

Täuscher

et al. 2022

Langmuir

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Hierarchical assemblies of functional polymer particles are promising due to their surface as well as physicochemical properties. However, hierarchical composites are complex and challenging to form due to the many steps necessary for integrating different components into one system. Highly structured four-level composite particles were formed in a four-step process. First of all, gold (Au) nanoparticles, poly(methyl methacrylate) (PMMA) nanoparticles, and poly(tripropylene glycol diacrylate) (poly-TPGDA) microparticles were individually synthesized. By applying microfluidic techniques, polymer nano- and microparticles were formed with tunable size and surface properties. Afterwards, the negatively charged gold nanoparticles and PMMA particles functionalized with a positively charged surface were mixed to form Au/PMMA assemblies. The Au/PMMA composites were mixed and incubated with poly-TPGDA microparticles to form ternary Au/PMMA/poly-TPGDA assemblies. For the formation of composite-containing microparticles, Au/PMMA/poly-TPGDA composites were dispersed in an aqueous acrylamide–methylenebisacrylamide solution. Monomer droplets were formed in a co-flow microfluidic device and photopolymerized by UV light. In this way, hierarchically structured four-level composites consisting of four different size ranges0.025/0.8/30/1000 μmwere obtained. By functionalizing polymer nano- and microparticles with different fluorescent dyes, it was possible to visualize the same composite particle under two different excitation modes (λex = 395–440 and λex = 510–560 nm). The Au/PMMA/poly-TPGDA composite-embedded polyacrylamide microparticles can be potentially used as a model for the creation of composite particles for sensing, catalysis, multilabeling, and biomedical applications.

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“…In this regard, microfluidics is a very promising platform that can be able to produce metal‐polymer composite particles of uniform size and composition. [ 36–39 ]…”

Section: Introductionmentioning

confidence: 99%

“…In this regard, microfluidics is a very promising platform that can be able to produce metal-polymer composite particles of uniform size and composition. [36][37][38][39] Microfluidics or lab-on-a-chip technique is a versatile reaction technique that deals with a small volume (droplets of picoliter or nanoliter) of liquid in the tiny microchannel. [40][41][42] Inside microfluidics, efficient reactant mixing and tunable composition can be realized that finally allow generation of uniform products with lower polydispersity.…”

mentioning

confidence: 99%

Stationary, Continuous, and Sequential Surface‐Enhanced Raman Scattering Sensing Based on the Nanoscale and Microscale Polymer‐Metal Composite Sensor Particles through Microfluidics: A Review

Visaveliya

Mazetyte‐Stasinskiene

Köhler

2022

Advanced Optical Materials

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Surface‐enhanced Raman scattering (SERS) is a label‐free and accurate analytical technique for the detection of a broad range of various analytes such as, biomolecules, pesticides, petrochemicals, as well as, cellular and other biological systems. A key component for the SERS analysis is the substrate which is required to be equipped with plasmonic features of metal nanostructures that directly interact with light and targeted analytes. Either metal nanoparticles can be deposited on the solid support (glass or silicon) which is suitable for stationary SERS analysis or dispersed in the solution (freely moving nanoparticles). Besides these routinely utilizing SERS substrates, polymer–metal composite particles are promising for sustained SERS analysis where metal nanoparticles act as plasmon‐active (hence SERS‐active) components and polymer particles act as support to the metal nanoparticles. Composite sensor particles provide 3D interaction possibilities for analytes, suitable for stationary, continuous, and sequential analysis, and they are reusable/regenerated. Therefore, this review is focused on the experimental procedures for the development of multiscale, uniform, and reproducible composite sensor particles together with their application for SERS analysis. The microfluidic reaction technique is highly versatile in the production of uniform and size‐tunable composite particles, as well as, for conducting SERS analysis.

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Microfluidic fabrication of fluorescent nanomaterials: A review

Cited by 39 publications

References 139 publications

Unlocking All-Solid Ion Selective Electrodes: Prospects in Crop Detection

Unlocking All-Solid Ion Selective Electrodes: Prospects in Crop Detection

Four-Level Structural Hierarchy: Microfluidically Supported Synthesis of Polymer Particle Architectures Incorporating Fluorescence-Labeled Components and Metal Nanoparticles

Stationary, Continuous, and Sequential Surface‐Enhanced Raman Scattering Sensing Based on the Nanoscale and Microscale Polymer‐Metal Composite Sensor Particles through Microfluidics: A Review

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