“…Despite the requirement of extensive effort in designing six sets of primers, LAMP can be easily integrated with lab on a chip devices to perform the detection process, which clearly applicable in the development of biosensor and POC monitoring devices (Mori et al, 2001., Notomi et al, 2000. LAMP amplicon were detected utilizing turbidity (Mori et al, 2001), electrochemical (Ahmed et al, 2009, Safavieh et al 2012a, gel electrophoresis (Le et al, 2012), fluorescence (Hong et al, 2012, Safavieh et al, 2012b, Safavieh et al,2014a, lateral flow test and magnetic beads (Roy, S et al, 2016). All these detection modalities have a major drawback in providing significant difference between positive and negative samples, which yields difficulties in quantitative analysis of nucleic acids.…”