Microfluidic chip based chemiluminescence detection of L-phenylalanine in pharmaceutical and soft drinks

A Review on Electrochemical Sensors and Biosensors Used in Phenylalanine Electroanalysis

“…In determining the essential amino acid Phe, optical methods were used, respectively: colorimetry [22,23]. UV and IR spectrophotometry [24], fluorescence [25][26][27][28][29], enhanced fluorescence [30], chemiluminescence [31][32][33]; separation methods, such as: gas chromatography [34], capillary electrophoresis, HPLC-high performance liquid chromatography [22,[35][36][37][38][39][40][41][42][43][44]; spectroscopic methods: Raman spectroscopy [45,46], laser-assisted spectroscopy [47], UV-Vis spectroscopy and chemometry [48]; UV−Vis and surface-enhanced Raman scattering [49], nuclear magnetic resonance [50] and circular dichroism spectroscopy [51]; mass spectrometry [22,34,41,52], fluorimetry [53].…”

Utilisation of micro- and nanoscaled materials in microfluidic analytical devices

“…Also, low fabrication cost, in some cases biocompatibility, the possibility of miniaturisation, reduced volume of waste, easy customisation and transportation are other advantages. Thanks to these properties allowing microchannels to be practical handy devices, microfluidic chips may be applied in clinical diagnostics, especially in point-of-care testing [2,9,10], environment monitoring [11][12][13], food, agriculture and biosystems industries [14][15][16] or biochemical kinetic studies [17][18][19]. Although microchannels have numerous advantages and show a real potential for routine laboratory or in situ applications as illustrated in this review, their success within the commercial sphere is still minimal.…”

A review on microfluidics in the detection of food pesticide residues

“…At the same time, the irony is that these methods often require a large amount of solvent, which can cause additional environmental problems in the process of monitoring pollutants . With the rapid advancement of microelectro‐mechanical systems processing technology, a microfluidic technology that integrates the processes of injection, reaction, and detection in biochemical samples into one device has attracted extensive attention from experts and scholars in the field of pesticide residue detection . American scholar Duford et al.…”