Microfat Grafting in Nasal Surgery

Erol, Onur

doi:10.1177/1090820x14529444

Cited by 25 publications

(28 citation statements)

References 56 publications

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“…11 The application of these technical details mostly depends on the individual experience and preference of the senior surgeons rather than evidence-based data obtained by experimental studies. 1,3,12,13 The presented study focuses on an important issue in fat harvesting and questions the necessity of tumescent solution usage before fat graft harvest. It will be beneficial to find out whether the local anesthetics or vasoconstrictor agents used in the tumescent solution pose any harm against the harvested fat grafts.…”

Section: Discussionmentioning

confidence: 99%

“…There are only a few experimental or clinical studies focused on this subject, and mostly some expert opinion was reported in the literature. 1,[13][14][15][16] In this article, long-term clinical and histopathologic effects of the tumescent solutions containing different combinations of lidocaine and adrenaline were investigated in a rat model.…”

Section: Discussionmentioning

confidence: 99%

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Effects of Tumescent Solution on Fat Survival

et al. 2017

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Autologous fat transfer is a commonly used procedure in plastic surgery practice. The long-term survival rate of fat grafts is the most important issue for satisfactory results. The presented study includes the effects of different tumescent solutions on long-term fat graft survival. A total of 24 rats were divided into four groups: sham, lidocaine, adrenaline, and lidocaine + adrenaline groups. In all groups except the sham group, right inguinal fat pad was harvested 10 minutes after injecting 5 cc of the appropriate tumescent solution. The fat pad was trimmed and reimplanted to the interscapular area. After 3 months, fat pad was reharvested and sent for histopathologic evaluation. The harvested fat grafts were weighted in both surgical sessions. A significant difference was observed in comparison of fat grafts weights between the initial operation and the postoperative third month (p = 0.002). By intergroup comparisons, a significant difference was observed between sham and adrenaline groups (p = 0.002) and between sham and lidocaine + adrenaline groups (p = 0.007). No statistical difference was observed by the comparison of TUNNEL results (p = 0.663). The histopathologic evaluation of the specimens revealed similar results between groups. The injection of tumescent solutions containing only lidocaine before fat harvesting yields similar long-term fat graft survival rates in comparison to the conduction of surgical procedure without injecting any tumescent fluid. However, the injection of solutions containing adrenaline with or without lidocaine may decrease the long-term survival rates of fat autografts.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Effects of Tumescent Solution on Fat Survival

et al. 2017

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“…Specifically, these studies involved fat grafting (1) in the refinement of cleft nose; 14 (2) as a complementary procedure during open rhinoplasty; 15 (3) in the presence/absence of rhinoplasty; 16 (4) as a means of restoring volume in reconstructive surgery; 17 (5) to treat sequelae of rhinoplasty; 18 (6) in terms of microfat injection to treat secondary nasal deformities; 19 (7) to correct complications of rhinoplasty; 20 and (8) as a potential cause of nasal-tip numbness after lipofilling. 21 In Table 1, we summarize the key findings and the benefits and drawbacks of each of these studies.…”

Section: Resultsmentioning

confidence: 99%

Microautologous Fat Transplantation for Primary Augmentation Rhinoplasty: Long-Term Monitoring of 198 Asian Patients

Kao

Lin

et al. 2016

Aesthet Surg J

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BackgroundNumerous techniques and materials are available for increasing the dorsal height and length of the nose. Microautologous fat transplantation (MAFT) may be an appropriate strategy for augmentation rhinoplasty.ObjectivesThe authors sought to determine the long-term results of MAFT with the so-called one-third maneuver in Asian patients who underwent augmentation rhinoplasty.MethodsA total of 198 patients who underwent primary augmentation rhinoplasty with MAFT were evaluated in a retrospective study. Fat was harvested by liposuction and was processed and refined by centrifugation. Minute parcels of purified fat were transplanted to the nasal dorsum with a MAFT-Gun. Patient satisfaction was scored with a 5-point Likert scale, and aesthetic outcomes were validated with pre- and postoperative photographs.ResultsThe mean age of the patients was 45.5 years. The mean operating time for MAFT was 25 minutes, and patients underwent 1-3 MAFT sessions. The mean volume of fat delivered per session was 3.4 mL (range, 2.0-5.5 mL). Patients received follow-up for an average of 19 months (range, 6-42 months). Overall, 125 of 198 patients (63.1%) indicated that they were satisfied with the results of 1-3 sessions of MAFT. There were no major complications.ConclusionsThe results of this study support MAFT as an appropriate fat-transfer strategy for Asian patients undergoing primary augmentation rhinoplasty.Level of Evidence: 4 Therapeutic

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“…Smaller particles harbor more cytolysis and larger particles may lead to significant central necrosis of transplants. 15,24,25…”

Section: Benefits Of Direct Fat Harvestingmentioning

confidence: 99%

Optimization of the Soft Tissue Envelope of the Nose in Rhinoplasty Utilizing Fat Transfer Combined with Platelet-Rich Fibrin

et al. 2021

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A thin or damaged skin soft tissue envelope may cause concerns in primary and secondary rhinoplasty. During postoperative healing, unpredictable scarring and contraction may occur and lead to significant aesthetic and trophic sequelae. Besides a meticulous surgical technique, there are no reliable techniques to prevent long-term skin damage and shrinkage. Fat transfer with addition of platelet-rich fibrin (PRF) harbors the possibility of local soft tissue regeneration and skin rejuvenation through growth factors and mesenchymal stem cells. It may also facilitate the creation of a thin fat layer on the dorsum to prevent shrink-wrap forces and conceal small irregularities. The goal is to provide evidence for the feasibility, durability, and beneficial effect of diced macrofat transfer bonded with PRF on the nasal dorsum. We present the technique of fat transfer conjugated with PRF as a nasal dorsal graft. Clinical endpoints were the prevention of trophic disturbances and atrophy at a 1-year postoperative follow-up. We present the skin mobility test as a clinical indicator of a healthy soft tissue envelope. The presented case series consists of 107 rhinoplasties. Fat was harvested in the umbilical or costal region. PRF was created by centrifugation of autologous whole blood samples. Macrofat was diced, cleaned, and bonded with PRF. The compound transplants were transferred to the nasal dorsum. There were no perioperative complications or wound-healing issues. Mean follow-up was 14 months. Clinical inspection showed good skin quality and no signs of shrinkage, marked scarring, or color changes with positive skin mobility test in all patients. Survival of fat was confirmed by ultrasonography and magnetic resonance imaging. Diced macrofat transfer in conjunction with PRF to the nasal dorsum is a feasible and safe method. A beneficial effect on the soft tissue envelope is demonstrated as well as the prevention of shrink-wrap forces.

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Microfat Grafting in Nasal Surgery

Abstract: 4.

Cited by 25 publications

References 56 publications

Effects of Tumescent Solution on Fat Survival

Effects of Tumescent Solution on Fat Survival

Microautologous Fat Transplantation for Primary Augmentation Rhinoplasty: Long-Term Monitoring of 198 Asian Patients

Optimization of the Soft Tissue Envelope of the Nose in Rhinoplasty Utilizing Fat Transfer Combined with Platelet-Rich Fibrin

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