Microextraction by packed sorbent using a new restricted molecularly imprinted polymer for the determination of estrogens from human urine samples

Oliveira, Hanna Leijoto de; Teixeira, Leila Suleimara; Dinali, Laíse Aparecida Fonseca; Pires, Bruna Carneiro; Simões, Nathália Soares; Borges, Keyller Bastos

doi:10.1016/j.microc.2019.104162

Cited by 38 publications

(6 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Oliveira et al ( 2019a , 2019b ) in 2019 reported two new methods in different papers for successfully determination of estrogens such as estriol (E3) and estrone (E1) from human urine by Restricted Access Mesoporous Molecularly Imprinted Polymer double coated with Hydrophilic Monomer and Bovine Serum Albumin (RA-MMIP-HM-BSA/HPLC–UV) method and ethinylestradiol (EE2) and estradiol (E2) from human urine by Restricted Access Material combined to Molecularly Imprinted Polymer for selective Magnetic Solid-Phase Extraction (RAM-MIP-MSPE/HPLC–UV) method. The first developed method was linear for each hormone in the concentration range of 100–1100 ng mL −1 , with correlation coefficients of 0.9952 and 0.9954 for E3 and E1, respectively and the second improved technique produced linearity for each hormone across the concentration range of 80–1100 ng mL −1 , with correlation coefficients of 0.9954 and 0.9971 for E2 and EE2, respectively.…”

Section: Mip In Bioanalysismentioning

confidence: 99%

Recent molecularly imprinted polymers applications in bioanalysis

Suzaei¹,

Daryanavard

Abdel-Rehim

et al. 2022

Chem. Pap.

View full text Add to dashboard Cite

Molecular imprinted polymers (MIPs) as extraordinary compounds with unique features have presented a wide range of applications and benefits to researchers. In particular when used as a sorbent in sample preparation methods for the analysis of biological samples and complex matrices. Its application in the extraction of medicinal species has attracted much attention and a growing interest. This review focus on articles and research that deals with the application of MIPs in the analysis of components such as biomarkers, drugs, hormones, blockers and inhibitors, especially in biological matrices. The studies based on MIP applications in bioanalysis and the deployment of MIPs in high-throughput settings and optimization of extraction methods are presented. A review of more than 200 articles and research works clearly shows that the superiority of MIP techniques lies in high accuracy, reproducibility, sensitivity, speed and cost effectiveness which make them suitable for clinical usage. Furthermore, this review present MIP-based extraction techniques and MIP-biosensors which are categorized on their classes based on common properties of target components. Extraction methods, studied sample matrices, target analytes, analytical techniques and their results for each study are described. Investigations indicate satisfactory results using MIP-based bioanalysis. According to the increasing number of studies on method development over the last decade, the use of MIPs in bioanalysis is growing and will further expand the scope of MIP applications for less studied samples and analytes.

show abstract

Section: Mip In Bioanalysismentioning

confidence: 99%

Recent molecularly imprinted polymers applications in bioanalysis

Suzaei¹,

Daryanavard

Abdel-Rehim

et al. 2022

Chem. Pap.

View full text Add to dashboard Cite

show abstract

“…The molecularly imprinted sorbents found an application in biomedical or clinical investigations of the levels of various important biomolecules, such as biogenic amines dopamine in human urine [ 151 ], tryptamine in human cerebrospinal fluid [ 152 ], psychoactive compounds such as cocaine [ 153 ] or cannabinoids [ 154 ], estrogens [ 155 ], various drugs such as gliclazide [ 156 ], nadifloxacin [ 157 ], phenytoin [ 158 ], zolpidem [ 159 ], and pramipexole [ 160 ] among others. Finally, molecularly imprinted sorbents were also used to monitor in vivo in animal model metabolites of the pharmacologically active compounds of plant origin such as hesperetin, a flavonoid, possessing antioxidant, anti-cancer, anti-inflammatory, cardiovascular protection and anti-rheumatic activities [ 161 ].…”

Section: Application Potential Of Imprinted Sorbentsmentioning

confidence: 99%

Imprinting Technology for Effective Sorbent Fabrication: Current State-of-Art and Future Prospects

2021

View full text Add to dashboard Cite

In the last 10 years, we have witnessed an extensive development of instrumental techniques in analytical methods for determination of various molecules and ions at very low concentrations. Nevertheless, the presence of interfering components of complex samples hampered the applicability of new analytical strategies. Thus, additional sample pre-treatment steps were proposed to overcome the problem. Solid sorbents were used for clean-up samples but insufficient selectivity of commercial materials limited their utility. Here, the application of molecularly imprinted polymers (MIPs) or ion-imprinted polymers (IIPs) in the separation processes have recently attracted attention due to their many advantages, such as high selectivity, robustness, and low costs of the fabrication process. Bulk or monoliths, microspheres and core-shell materials, magnetically susceptible and stir-bar imprinted materials are applicable to different modes of solid-phase extraction to determine target analytes and ions in a very complex environment such as blood, urine, soil, or food. The capability to perform a specific separation of enantiomers is a substantial advantage in clinical analysis. The ion-imprinted sorbents gained interest in trace analysis of pollutants in environmental samples. In this review, the current synthetic approaches for the preparation of MIPs and IIPs are comprehensively discussed together with a detailed characterization of respective materials. Furthermore, the use of sorbents in environmental, food, and biomedical analyses will be emphasized to point out current limits and highlight the future prospects for further development in the field.

show abstract

“…MEPS is commercially available and was reviewed recently. , Recent applications include among other extraction of opiates from whole blood combined with gas chromatography/tandem mass spectrometry and extraction of the new psychoactive substance dichloropane from saliva combined with ion mobility spectrometry . New extraction phases have also been developed and tested with MEPS, including polyacrylonitrile/graphene oxide nanofibers for extraction of drugs from human plasma, and a restricted molecularly imprinted polymer for extraction of estrogens from human urine …”

Section: Micro Solid-phase Extraction and Microextraction By Packed S...mentioning

confidence: 99%

“…187 New extraction phases have also been developed and tested with MEPS, including polyacrylonitrile/graphene oxide nanofibers for extraction of drugs from human plasma, 188 and a restricted molecularly imprinted polymer for extraction of estrogens from human urine. 189 ■ DISPERSIVE SOLID-PHASE MICROEXTRACTION Dispersive solid-phase microextraction (DSPME), alternatively termed dispersive microsolid phase extraction (D-μSPE), is based on dispersion of solid extraction phase (sorbent) in the sample. After extraction, the sorbent is separated from the sample by centrifugation, and the analytes can be desorbed either using a solvent or using heat (thermal desorption).…”

Section: ■ Stir-bar Sorptive Extractionmentioning

confidence: 99%