“…315,316 Increment of proPO and RB activities were also evident along with the significant increase in THC in treated shrimps compared to the untreated controls. 121,128,194,285,315,317,318 Besides, the expression of immune genes, such as Pen-3a, HSP-70, STAT, ALF, and proPO, were upregulated as a result of prebiotic inclusion. 41,50,193 A higher survival rate was also observed in the prebiotic treatment group when the shrimps were challenged with pathogens such as A.hydrophila, 313 Vibrio parahaemolyticus, 295 V.harveyi, 194 Vibrio alginolyticus, and white spot syndrome virus (WSSV).…”