“…Among them, focusing on image segmentation and specification of regions of interest (ROI), several methods have been proposed, such as classical image filter and local threshold [3,4], and techniques based on mathematical morphology [5], fractal models [6], optimal filters [7], wavelet analysis and multi-scale analysis [3]. Various classification approaches have also been presented to characterize MCs, such as rule-based systems [8], fuzzy logic systems [9,10], statistical methods based on Markov random fields(MRF) [11], and support vector machines [12]. In the past decade, most of the work reported in the literatures has employed neural networks in MCs characterization [5,13,14].…”