Microbiology of Chronic Frontal Sinusitis

Schlosser, Rodney J.; London, Scott D.; Gwaltney, Jack M.; Gross, Charles W.

doi:10.1097/00005537-200108000-00004

Cited by 36 publications

(20 citation statements)

References 12 publications

(18 reference statements)

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“…Accordingly, our literature review revealed that the different studies used a diversity of sampling methods (swabs, aspiration, molecular techniques) and sampling sites (middle meatus, maxillary sinus, other ethmoidal bulla, and frontal sinus), but none identified a distinct pattern of bacterial growth or a specific culprit species. The results of the most recent publications are summarized in table 1 [11,12,13,14,15,27,28,29]. …”

Section: Discussionmentioning

confidence: 99%

Bacteriology of the Middle Meatus in Chronic Rhinosinusitis with and without Polyposis

Stern

Hadar²,

Nachalon³

et al. 2016

ORL

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There are only limited data in the literature, and none specifically from the Middle East, on the pathogenic bacteria in chronic rhinosinusitis (CRS) as opposed to healthy nasal cavities and their association with disease severity. The present study was conducted in the department of head and neck surgery of a tertiary medical center. Middle meatal swabs were taken preoperatively from patients with CRS with nasal polyposis (CRSwNP) (n = 60), CRS without nasal polyposis (CRSsNP) (n = 50), and control patients with septal deviation (n = 26) or no nasal abnormalities (n = 27). Culture findings were compared among the groups and correlated with CRS severity. Positive pathogenic culture rates were 78% in the CRSwNP group and 64% in the CRSsNP group. Twenty pathogenic bacterial species were identified; the most common was Staphylococcus aureus (27%). The most common Gram-negative isolate was Citrobacter spp. (17%). Gram-negative species were significantly more prevalent in the CRSwNP group than the others. Mean Lund-Mackay scores were 12.8 in the CRSwNP group and 6.9 in the CRSsNP group, and were unrelated to the culture findings. Positive culture rates were significantly higher in the septal deviation (54%) than the nasal healthy group (26%), although both values were significantly lower than in the CRS groups. In conclusion, patients with CRS have higher rates of bacterial isolates than patients without CRS. CRSwNP is associated with more Gram-negative bacteria than CRSsNP, regardless of disease severity. The relatively high positive culture rate in patients with septal deviation merits investigation.

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Section: Discussionmentioning

confidence: 99%

Bacteriology of the Middle Meatus in Chronic Rhinosinusitis with and without Polyposis

Stern

Hadar²,

Nachalon³

et al. 2016

ORL

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“…42 The interactions between the bacteria related to chronic frontal sinusitis 43 and BAG have not been studied but, in principle, the experimentally shown antibacterial properties of BAG 35,36 can promote the clinical outcome of obliterated sinuses after chronic infection. Probably the antibacterial properties of BAG can provide extraordinarily favorable conditions for an uneventful healing process in a chronically infected environment.…”

Section: Discussionmentioning

confidence: 99%

Bioactive glass S53P4 in frontal sinus obliteration: A long‐term clinical experience

et al. 2006

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“…13 On this basis, initial antibiotic therapy for chronic frontal sinusitis does not significantly differ from that for acute bacterial frontal sinusitis, with amoxicillin with clavulanate providing adequate coverage on an empiric basis, albeit for longer initial durations. Although the microbiology of acute bacterial frontal sinusitis lends itself to narrow-spectrum antimicrobial therapy, antibiotic therapy for either initial medical management or acute exacerbations of chronic frontal sinusitis may require broader-spectrum therapy and also may be more likely to result in treatment failures.…”

Section: Antibiotic Therapymentioning

confidence: 99%