Microbiology and antimicrobial therapy of peri‐implantitis

Mombelli, Andrea

doi:10.1034/j.1600-0757.2002.280107.x

Cited by 221 publications

(242 citation statements)

References 61 publications

Supporting

Mentioning

198

Contrasting

Unclassified

Order By: Relevance

“…In a dental implant-supported fixed prosthesis, the microbial colonization begins at prosthetic areas exposed to the oral environment taking into account that biofilm formation depends on the prosthetic design, surface conditions, and on the oral microbiota [41,66,67,88]. After implantation, a part of the margin area of implant fixture is in contact with connective and epithelial tissues, while another part is in contact with abutment and oral fluids.…”

Section: Presence Of Oral Biofilmsmentioning

confidence: 99%

Wear and Corrosion Interactions on Titanium in Oral Environment: Literature Review

et al. 2015

View full text Add to dashboard Cite

The oral cavity is a complex environment where corrosive substances from dietary, human saliva, and oral biofilms may accumulate in retentive areas of dental implant systems and prostheses promoting corrosion at their surfaces. Additionally, during mastication, micromovements may occur between prosthetic joints causing a relative motion between contacting surfaces, leading to wear. Both processes (wear and corrosion) result in a biotribocorrosion system once that occurs in contact with biological tissues and fluids. This review paper is focused on the aspects related to the corrosion and wear behavior of titanium-based structures in the oral environment. Furthermore, the clinical relevance of the oral environment is focused on the harmful effect that acidic substances and biofilms, formed in human saliva, may have on titanium surfaces. In fact, a progressive degradation of titanium by wear and corrosion (tribocorrosion) mechanisms can take place affecting the performance of titanium-based implant and prostheses. Also, the formation of wear debris and metallic ions due to the tribocorrosion phenomena can become toxic for human tissues. This review gathers knowledge from areas like materials sciences, microbiology, and dentistry contributing to a better understanding of bio-tribocorrosion processes in the oral environment.

show abstract

Section: Presence Of Oral Biofilmsmentioning

confidence: 99%

Wear and Corrosion Interactions on Titanium in Oral Environment: Literature Review

et al. 2015

View full text Add to dashboard Cite

show abstract

“…Disrupted relationship between host and microflora resulting in disease of the oral structures, mainly include dental caries, gingivitis or periodontitis or peri-implantitis [22]. Peri-implantitis around osseointegrated implants initiated by bacterial infection affect the soft and hard tissues and can lead to bone damage [23]. Some bacteria attached to implanted restorative materials form the biofilm that protects them against antibiotic treatment, leading to antibiotic-resistant periprosthetic infection [24].…”

Section: Discussionmentioning

confidence: 99%

In vitro biocompatibility of anodized titanium with deposited silver nanodendrites

et al. 2016

View full text Add to dashboard Cite

Engineers searching new dental biomaterials try to modify the structure of the material in order to achieve the best performance as well as increased migration and proliferation of cells involved in the osseointegration of the implant. In this work we show in vitro test results of the Ti, which was anodically oxidized at high voltages with additionally deposited silver in the form of nanodendrites. The in vitro cytocompatibility of these materials was evaluated and compared with a conventional microcrystalline titanium. During the studies, established cell line of human gingival fibroblasts (HGF) and osteoblasts were cultured in the presence of tested materials, and its survival rate and proliferation activity were examined. Titanium samples modified with silver has a higher degree of biocompatibility in comparison with the unmodified reference material. Cells in contact with studied material showed a higher relative viability potential, stable level of proliferation activity, and lower rate of mortality. Biocompatibility tests carried out indicate that the anodically oxidized titanium at high voltages with additionally deposited nanosilver could be a possible candidate for dental implants and other medicinal applications.

show abstract

“…PCR is also reproducible and relatively easy to execute as well as particularly valuable in the detection of non-cultivable organisms or those that are difficult to be distinguished in the cultivation 4,28 . The peri-implant sites of patients with periodontitis can present high concentrations of pathogens in the periodontal pockets 2,10,19,30 . Therefore, periodontal lesions considered irreversible can determine the indication of extraction of unhealthy teeth to avoid infection of future peri-implant sites 8 .…”

Section: Discussionmentioning

confidence: 99%

Analysis of the presence of pathogens which predict the risk of disease at peri-implant sites through polymerase chain reaction (PCR)

et al. 2005

View full text Add to dashboard Cite

ABSTRACT:The presence of DNA of Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, and Prevotella intermedia in the peri-implant sulcus samples of 19 partially edentulous patients was analyzed by polymerase chain reaction (PCR) and related to the depth of the peri-implant sulcus, bleeding on probing, and probable risk of disease. Ten of those patients presented a history of periodontal disease and nine of those did not. The DNA amplification of these pathogens was observed in seven samples, of which four were from patients without history of periodontal disease. The results suggest that even when significant inflammatory signs are absent the qualitative detection may indicate risk of peri-implantitis, requiring more strict postoperative control. DESCRIPTORS: Actinobacillus actinomycetemcomitans; Porphyromonas gingivalis; Prevotella intermedia; PCR.RESUMO: A presença dos ADN de Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis e Prevotella intermedia em amostras coletadas de sulco periimplantar de 19 pacientes parcialmente desdentados foi analisada pela reação em cadeia da polimerase (PCR). Dentre esses 19 pacientes, dez apresentavam histórico de doença periodontal e nove não apresentavam antecedentes. Os resultados obtidos nesta análise foram relacionados com a profundidade do sulco periimplantar, o sangramento à sondagem e o provável risco de doença. Constatou-se que houve a amplificação do ADN das bactérias-alvo em sete amostras, sendo quatro de pacientes sem histórico de periodontopatia. Este resultado sugere que mesmo na ausência de sinais inflamatórios significantes, essa detecção qualitativa pode indicar risco de periimplantite, requerendo manutenção pós-operatória mais rigorosa.

show abstract

Microbiology and antimicrobial therapy of peri‐implantitis

Cited by 221 publications

References 61 publications

Wear and Corrosion Interactions on Titanium in Oral Environment: Literature Review

Wear and Corrosion Interactions on Titanium in Oral Environment: Literature Review

In vitro biocompatibility of anodized titanium with deposited silver nanodendrites

Analysis of the presence of pathogens which predict the risk of disease at peri-implant sites through polymerase chain reaction (PCR)

Contact Info

Product

Resources

About