Microbiological Studies on the Production of Antimicrobial Agent by Saponin Aloe vera Linn Against Streptococcus sanguinis

Berniyanti, Titiek; Mahmiyah, Erma

doi:10.3923/jm.2015.385.392

Cited by 4 publications

(4 citation statements)

References 2 publications

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“…michiganensis was exclusively sensitive to the TPGs among all the tested bacterial species (Supplementary Table S1 ). The results also support the hypothesis that the inhibitory effect of saponins may vary depending on the microorganisms; Gram-positive bacteria comprised of a single layered cell wall are more sensitive to saponins than Gram-negative bacteria because saponin molecules are likely involved in the mechanical damage of Gram-positive bacteria cell membranes 39 .…”

Section: Discussionsupporting

confidence: 77%

Identification of novel compounds, oleanane- and ursane-type triterpene glycosides, from Trevesia palmata: their biocontrol activity against phytopathogenic fungi

Kim

Han

Ngo

et al. 2018

Sci Rep

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Plants contain a number of bioactive compounds that exhibit antimicrobial activity, which can be recognized as an important source of agrochemicals for plant disease control. As part of our search for new antimicrobial agents from natural sources, we found that a crude methanol extract of Trevesia palmata exhibited a promising antifungal activity against phytopathogenic fungi, such as Magnaporthe oryzae and Botrytis cinerea. Furthermore, based on activity-guided fractionation, we isolated five antifungal compounds from the methanol extract of T. palmata: two new triterpene glycosides (TPGs), TPG1 (hederagenin-3-O-β-D-glucopyranosyl-(1 → 3)-α-L-rhamnopyranosyl-(1 → 2)-α-L-rhamnopyranosyl-(1 → 2)-α-L-arabinopyranoside) and TPG5 (3-O-α-L-rhamnopyranosyl asiatic acid), along with three known TPGs (TPG2 [macranthoside A], TPG3 [α-hederin], and TPG4 [ilekudinoside D]). The chemical structures of the TPGs were determined by spectroscopic analyses and by comparison with literature data. An in vitro antifungal bioassay revealed that except for TPG4 (ilekudinoside D; IC50 >256 μg/ml), the other TPGs exhibited strong antifungal activities against the rice blast pathogen M. oryzae with IC50 values ranging from 2–5 μg/ml. In particular, when the plants were treated with compound TPG1 (500 μg/ml), disease control values against rice blast, tomato grey mold, tomato late blight, and wheat leaf rust were 84, 82, 88, and 70%, respectively, compared to the non-treatment control. Considering the in vitro and in vivo antifungal activities of the TPGs and the T. palmata methanol extracts, our results suggest that T. palmata can be a useful source to develop new natural fungicides.

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Section: Discussionsupporting

confidence: 77%

Identification of novel compounds, oleanane- and ursane-type triterpene glycosides, from Trevesia palmata: their biocontrol activity against phytopathogenic fungi

Kim

Han

Ngo

et al. 2018

Sci Rep

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“…Bahan herbal memiliki sifat anti inflamasi yang dapat menstimulasi respons imun, memiliki sifat anti perdarahan, sebagai bahan antiseptik alami, serta memiliki sifat analgetik. 10 Pasta gigi herbal terbukti mampu mengatasi plak lebih baik dibandingkan pasta gigi non herbal. Sodium bikarbonat, Sodium florida dan kandungan bahan herbal terkandung dalam pasta gigi herbal.…”

Section: Andalas Dental Journalunclassified

Pasta Gigi Lidah Buaya (Aloe vera) sebagai Alternatif Herbal Untuk Kesehatan Gigi dan Mulut

Wiguna¹,

Murniwati²,

Suprianto³

2022

Andalas Dent. J.

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Background: Dental and oral health have an important role on overall body health, because it can affect someone's physical and psychological condition. The common tooth and mouth disease is periodontal disease. The main cause of periodontal disease is due to the presence of colonizing microorganisms in dental plaque. Gingivitis is a periodontal disease that is commonly found in the community. Review: Aloe vera as an herbal plant has many benefits because of its properties, such as; antiseptic, antioxidant, anti-inflammatory, analgesic, antimicrobial, and wound healing. Purpose: The purpose of this literature review is to identify the potential use of Aloe vera toothpaste as an herbal alternative for oral health. Conclusion: Toothpaste containing Aloe vera has been shown to inhibit plaque formation, due to its saponin compound. Aloe vera toothpaste can also significantly reduce the gingival index.

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“…Saponin bereaksi pada gugus fosfat dalam fosfolipid membran sel dan kemudian dapat berpenetrasi ke dalam sel. Hal ini menyebabkan hilangnya permeabilitas serta denaturasi membrane sel, sehingga agen antibakteri lain dapat masuk ke dalam sel bakteri [30].…”

Section: Pendahuluanunclassified

Efektivitas Ekstrak Biji Srikaya (Annona squamosa L.) sebagai Bahan Pembersih Gigi Tiruan terhadap Daya Hambat Pertumbuhan Streptococcus mutans pada Basis Akrilik Heat Cured

Abdillah¹,

Soesetijo²,

Kristiana³

2020

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The rough surface of a heat cured acrylic resin as a denture base can cause a pathogenic buildup of plaques and biofilms, so an effort to clean the denture base is needed. The available denture cleaning chemicals are proof of some disadvantages, so it is necessary to do research on alternative natural ingredients. Srikaya seed extract using ethanol 96% solvent has been shown to have antibacterial activity and with its various properties, so that it has the potential to become denture cleaning agents. Samples were made based on ADA No.17 specifications with 5 samples in each of the 6 treatment groups, sampling using Simple Random Sampling. Samples contaminated with S. mutans were soaked in srikaya seed extract 25%, 50%, 75%, 100%, 0.5% NaOCl and sterile aquadest. There was a significant difference (p <0.05) in each treatment group. There is an influence of the difference in concentration of srikaya seed extract on the growth of S. mutans bacteria on a heat cured acrylic base. Keywords: heat cured acrylic resin, S.mutans, srikaya seed extract, absorbance

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Microbiological Studies on the Production of Antimicrobial Agent by Saponin Aloe vera Linn Against Streptococcus sanguinis

Cited by 4 publications

References 2 publications

Identification of novel compounds, oleanane- and ursane-type triterpene glycosides, from Trevesia palmata: their biocontrol activity against phytopathogenic fungi

Identification of novel compounds, oleanane- and ursane-type triterpene glycosides, from Trevesia palmata: their biocontrol activity against phytopathogenic fungi

Pasta Gigi Lidah Buaya (Aloe vera) sebagai Alternatif Herbal Untuk Kesehatan Gigi dan Mulut

Efektivitas Ekstrak Biji Srikaya (Annona squamosa L.) sebagai Bahan Pembersih Gigi Tiruan terhadap Daya Hambat Pertumbuhan Streptococcus mutans pada Basis Akrilik Heat Cured

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