Micro-fluidic analysis based on total internal light reflection

Sarov, Y.; Ivanov, Tzv.; Volland, Burkhard E.; Rangelow, Ivo W.

doi:10.1016/j.mee.2006.01.059

Cited by 6 publications

(6 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, the zeroth order response to RI changes is opposite for the case of s and p polarization, as observed and discussed above. In contrast, the sensing of strongly absorbing fluids shows that the DE η decreases with the fluidic absorption [19][20] for all diffraction orders and for any polarization direction. 16,17,20 The case considered in this paper samples combines these two cases; both the ERI and the EAI of the nanodispersions depend linearly on their concentration.…”

mentioning

confidence: 86%

“…[13][14] In our previous works, the first autonomous microrealization of a TIR-DG for uniform microfluid analysis is described. [19][20] Here, a TIR-DG is utilized for quantitative characterization of nanoparticle suspensions for the first time. A wide variety of liquid dispersions with polymeric, metallic, and ferromagnetic nanoparticles are investigated.…”

mentioning

confidence: 99%

“…As a result of the interference between these two types of reflected light, a diffraction pattern (8) is created. The diffraction efficiency (DE) of the zeroth order for a grating with 50% duty factor is given by 19 where r m and Φ m are the amplitude and the phase of the reflected light from the metal lines and Φ d is an additional phase shift due to the presence of a layer (5) which seals the grating. 20 Therefore, the substitution of eqs 1-2 in 3 proves the DE dependence on the fluidic optical constants.…”

mentioning

confidence: 99%

“…As such, TIR-DG offers advantages over GLRS because small variations in the fluidic RI are detected in real-time by changes in the diffracted light intensity without the need of any moving parts or spectral light analysis. GLRS has been already applied for liquids containing nanoparticles. − In our previous works, the first autonomous microrealization of a TIR-DG for uniform microfluid analysis is described. − Here, a TIR-DG is utilized for quantitative characterization of nanoparticle suspensions for the first time. A wide variety of liquid dispersions with polymeric, metallic, and ferromagnetic nanoparticles are investigated.…”

mentioning

confidence: 99%

“…The basic principles of the integrated sensor microfabrication are reported in our previous publications. − However, because nanoparticle dispersion analysis requires design modifications and improvements, a short summary of the microfabrication process is given here. The sensor is created by fitting together three Si <100> wafers, w1, w2, and w3 (Figure ).…”

mentioning

confidence: 99%

See 4 more Smart Citations

On Total Internal Reflection Investigation of Nanoparticles by Integrated Micro-Fluidic System

et al. 2007

View full text Add to dashboard Cite

We report on a novel sensor for characterization of nanoparticles colloidal suspensions. We employ a diffraction grating under total internal reflection for investigation of nanodisperse fluids passing through an integrated microfluidic channel. Dispersions containing polymeric, metallic, and ferromagnetic nanoparticles are studied. Using this device, we can accurately determine in real-time the specific refractive index for the nanoparticle suspension and the nanoparticle concentration. The nanoparticle concentrations can be calculated with a resolution of 0.3-0.5 wt% for polymeric nanoparticles, 0.03-0.05 wt% for metallic nanoparticles, and 0.05-0.1 wt% for ferromagnetic nanoparticles. This translates to an effective refractive index that can be determined with an accuracy of 7 x 10(-4) for the polymeric and 2 x 10(-4) for the metallic and ferromagnetic dispersions.

show abstract

mentioning

confidence: 86%

mentioning

confidence: 99%

mentioning

confidence: 99%