Micro-CT assessment of the effect of silver diammine fluoride on inhibition of root dentin demineralization

Shimizu, Miyuki; Matsui, Naoko; Sayed, Mahmoud; Hamba, Hidenori; Obayashi, Sho; Takahashi, Motoi; Tsuda, Yuka; Takagaki, Tomohiro; Nikaido, Toru; Tagami, Junji

doi:10.4012/dmj.2020-290

Cited by 5 publications

(1 citation statement)

References 37 publications

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“…Moreover, SDF promotes the remineralization of existing carious lesions and prevents the development of new lesions, as SDF reduces lesion depth and mineral loss [ 61 ] and increases microhardness after its application to the enamel [ 62 , 63 ] and dentin [ 64 , 65 ]. This remineralization ability also protects dental tissues against mechanical and chemical abrasion [ 66 , 67 ].…”

Section: Sdf’s Effectiveness Against Carious Lesionsmentioning

confidence: 99%

Clinical and primary evidence of silver diamine fluoride on root caries management

Hiraishi

Sayed

Takahashi

et al. 2022

Japanese Dental Science Review

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Root caries is a growing problem for the worldwide aging population. Silver diamine fluoride (SDF) contains high concentrations of silver and fluoride ions, which prevents and arrests root caries, as well as dentin caries in the primary teeth of young children. Unlike other fluoride products that mainly reduce the formation of new carious lesions, 38% SDF is an effective agent that can efficiently arrest the carious process, remineralize the decayed dental tissues, and protect the tooth structure against the formation of new caries lesions. The use of SDF can result in more caries-resistant tooth structures. Despite these merits, its clinical disadvantages are the deep penetration of silver ions and sequential formation of silver compounds, which cause esthetic concern due to the discoloration and impaired efficacy of dentin bonding after using SDF. Thus, this narrative review, by addressing the primary experimental results and clinical applications of SDF on root caries, proposes management methods for root caries in conjunction with the application of SDF. We propose a two-visit treatment protocol to take advantage of the SDF application for root surface caries and utilize the discoloration caused by SDF.

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Section: Sdf’s Effectiveness Against Carious Lesionsmentioning

confidence: 99%

Clinical and primary evidence of silver diamine fluoride on root caries management

Hiraishi

Sayed

Takahashi

et al. 2022

Japanese Dental Science Review

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Nano-CT characterization of dentinal tubule occlusion in SDF-treated dentin

Menzel,

Kiesow,

de Souza e Silva

2023

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Dentin hypersensitivity is an oral health concern affecting a large percentage of the world's adult population. Occlusion of the exposed dentinal tubules is among the treatment options available, and silver diammine fluoride (SDF) is an occluding agent used for interrupting or dampening the stimulus of the dental pulp nerves that produce pain. In addition to dentin permeability testing, the evaluation of desensitizing agents occluding dentinal tubules strongly relies on microscopic techniques, such as scanning electron microscopy (SEM). Limitations of SEM are that it provides only surface images that lack detailed information on the depth of penetration and amount of material present within the treated specimen, and it is prone to sample preparation artifacts. Here, we present high-resolution X-ray computed tomography (nano-CT) as a potential method for investigating dentin specimens with occluded tubules. We studied human dentin treated with SDF as an exemplary dentinal occlusion treatment option. We evaluated the silver deposits formed on the dentin surface region near the dentinal tubules and in the tubular regions using cross-section SEM, Energy Dispersive X-ray (EDX) analysis, and nano-CT. The resulting images obtained by SEM and nano-CT had comparable resolutions, and both techniques produced images of the tubules' occlusion. Nano-CT provided three-dimensional images adequate to quantitate tubule size and orientation in space. Moreover, it enabled clear visualization of dentinal tubules in any virtual plane and estimation of the amount and depth of occluding material. Thus, nano-CT has the potential to be a valuable technique for evaluating the occluding effects of virtually any material applied to dentinal tubules, supporting deciding between the best occluding treatment options.

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The effect of silver diamine fluoride on the microleakage of glass ionomer restoration in primary teeth at different time intervals

Zubair Jasim,

Saleem Khalaf

2023

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Silver diamine fluoride (SDF) has shown effectiveness in hardening tooth structure and killing bacteria. Therefore, it can be used to prevent and arrest dental caries. Riva Star (SDF) treatment alone will stop cavities but will not reverse the cavitation. The Silver Modified Atraumatic Procedure, often known as Smart, is the optimum technique for regaining the tooth's structure and function. Glass ionomer was introduced in (1972) as a new material that has become one of the most widely used materials in restorative dentistry. By releasing fluoride ions, this material has a therapeutic impact on the surrounding tooth structure. Microleakage is the ingress of bacteria, its byproducts, toxins, chemicals, oral fluids, and ions between the margins of the restoration and the cavity walls. Dental restoration lifetime is significantly influenced by microleakage at the toothrestoration contact. Material and method: In this study, we used 32 primary molars, class V cavities prepared on the buccal surface of all teeth. The teeth were divided into 2 groups: Group 1: 16 teeth treated with 38%SDF 8 of them restored directly with GIC filling and the other 8 restored after 14 days; Group 2: 16 teeth as control group left untreated with 38% SDF,8 teeth restored directly and 8 restored after 14 days. Samples were thermocycled, immersed in 2% methylene blue and then sectioned in a buccolingual direction. Dye penetration was measured with a digital camera connected to a stereo microscope. Result: results of this study showed a significant difference in microleakage between two-time intervals in which microleakage in GIC filling decreased at 14-day intervals than that of first-day interval in the experimental group, while in the control group, microleakage at 14 days intervals was higher than first-day interval, but it was not significant. Conclusion: Pretreatment of the primary teeth with SDF can decrease the microleakage of GIC restoration. If placed after 14 days, the microleakage would be lesser than that if the restoration was placed directly after SDF treatment. Therefore, it is recommended that SDF treatment be done, followed by a permanent restoration after 14 days, so the null hypothesis cannot be accepted. Keywords: Microleakage, Silver diamine fluoride, Glass ionomer filling, noninvasive dentistry

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Micro-CT assessment of the effect of silver diammine fluoride on inhibition of root dentin demineralization

Cited by 5 publications

References 37 publications

Clinical and primary evidence of silver diamine fluoride on root caries management

Clinical and primary evidence of silver diamine fluoride on root caries management

Nano-CT characterization of dentinal tubule occlusion in SDF-treated dentin

The effect of silver diamine fluoride on the microleakage of glass ionomer restoration in primary teeth at different time intervals

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