“…P. putida also has a broad potential to valorize lignocellulosic substrates (Anna Weimer et al, 2020). The rich metabolic network of the bacterium has been tailored for the bioproduction of polyhydroxyalkanoates (Poblete-Castro et al, 2013; Salvachúa et al, 2020), rhamnolipids (Tiso et al, 2020, p. 2), cis , cis -muconic acid (Bentley et al, 2020; Kohlstedt et al, 2018), pyruvate and lactate (Johnson and Beckham, 2015), isobutanol (Ankenbauer et al, 2021), or even fluorinated building-blocks (Calero et al, 2020). These and other advantageous characteristics including HV1 safety certification (Kampers et al, 2019), resistance to oxidative stress (Elmore et al, 2020; Guarnieri et al, 2017), suitability for large-scale aerobic fermentations (Ankenbauer et al, 2020), availability of high-quality genome-scale metabolic reconstruction (Nogales et al, 2020), or amenability to genetic manipulations with an available broad palette of engineering tools (Martínez-García and de Lorenzo, 2017) predetermine P. putida for the biotechnological upcycling of lignocellulosic substrates.…”