Methylmercury and Inorganic Mercury in Serum—Correlation to Fish Consumption and Dental Amalgam in a Cohort of Women Born in 1922

Bergdahl, Ingvar A.; Schütz, Andrejs; Ahlqwist, Margareta; Bengtsson, Calle; Lapidus, Leif; Lissner, Lauren; Hultén, B

doi:10.1006/enrs.1997.3820

Cited by 44 publications

(35 citation statements)

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“…Although concentrations in hair are most commonly used in epidemiological studies, whole-blood concentrations correlate well with hair concentrations (Björnberg et al, 2005). Two Swedish studies reported correlation coefficients around 0.50 between total fish consumption (from dietary interviews) and blood MeHg (Svensson et al, 1995;Bergdahl et al, 1998), which is only marginally higher than in this study.…”

Section: Discussioncontrasting

confidence: 54%

“…To the best of our knowledge, there are no studies in which the relationship between habitual fish consumption measured by an FFQ on whole diet and tissue concentrations of environmental contaminants has been assessed. Overall, studies on the relationship between fish consumption and environmental contaminants are scarce (Svensson et al, 1991(Svensson et al, , 1995Asplund et al, 1994;Bergdahl et al, 1998;Arisawa et al, 2003;Björnberg et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

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Dioxins, polychlorinated biphenyls, methyl mercury and omega-3 polyunsaturated fatty acids as biomarkers of fish consumption

et al. 2010

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Background/Objectives: To assess biomarkers and frequency questions as measures of fish consumption. Subjects/Methods: Participants in the Fishermen substudy numbered 125 men and 139 women (aged 22-74), and in the Health 2000 substudy, 577 men and 712 women (aged 45-74) participated. The aim of the Fishermen study was to examine the overall health effect of fish consumption in a high-consumption population, whereas the aim of the Health 2000 substudy was to obtain in-depth information on cardiovascular diseases and diabetes. Fish consumption was measured by the same validated food frequency questionnaire (FFQ) in both the studies, with a further two separate frequency questions used in the Fishermen substudy. Dioxins, polychlorinated biphenyls (PCBs) and methyl mercury (MeHg) (in the Fishermen substudy alone), and omega-3 polyunsaturated fatty acids (omega-3 PUFAs) (in both studies) were analyzed from fasting serum/blood samples. Results: The Spearman's correlation coefficients between FFQ fish consumption and dioxins, PCBs, MeHg and omega-3 PUFAs were respectively 0.46, 0.48, 0.43 and 0.38 among the Fishermen substudy men, and 0.28, 0.36, 0.45 and 0.31 among women. Similar correlation coefficients were observed between FFQ fish consumption and serum omega-3 PUFAs in the Health 2000 substudy, and also between FFQ fish consumption and the frequency questions on fish consumption in the Fishermen substudy. According to multiple regression modeling and LMG metrics, the most important fish consumption biomarkers were dioxins and PCBs among the men and MeHg among the women. Conclusions: Environmental contaminants seemed to be slightly better fish consumption biomarkers than omega-3 PUFAs in the Baltic Sea area. The separate frequency questions measured fish consumption equally well when compared with the FFQ.

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Section: Discussioncontrasting

confidence: 54%

Section: Introductionmentioning

confidence: 99%

Dioxins, polychlorinated biphenyls, methyl mercury and omega-3 polyunsaturated fatty acids as biomarkers of fish consumption

et al. 2010

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“…Bergdahl et coll. rapportent que la concentration en mercure plasmatique augmente en moyenne de 0,2 µg/L pour dix surfaces d'amalgame [16]. Notre travail montre que les porteurs d'amalgames ont une concentration médiane du mercure plasmatique sensiblement plus élevée que les non porteurs d'amalgame (0,38 µg/L vs 0,28 µg/L), mais cette différence sur un échantillon réduit n'est pas significative (p = 0,11).…”

Section: Discussionunclassified

Profil métallique sanguin chez des volontaires sains : 10 ans après

et al. 2013

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Résumé -Objectifs : Dix ans après avoir mesuré les concentrations normales d'une trentaine d'éléments métalliques dans le sang et le plasma, par plasma à couplage inductif relié à un détecteur de masse (ICP-MS), il nous a semblé utile d'évaluer l'impact des modifications éventuelles de notre environnement sur ces teneurs. Méthodes : Cent six personnels hospitaliers volontaires des deux sexes, indemnes de toute affection, sans exposition professionnelle aux métaux, non traités par du lithium ou du strontium, ne prenant pas d'oligo-élément ni de complément vitaminique, non porteurs de prothèse métallique, ont été inclus. La consommation de tabac et le port d'amalgame dentaire sont renseignés. Un dosage multiélémentaire de 26 métaux par ICP-MS (Li, Be, V, Cr, Mn, Co, Ni, Cu, Zn, As, Se, Rb, Sr, Mo, Ag, Cd, Sn, Te, Ba, W, Pt, Hg, TI, Pb, Bi et U) est effectué sur sang total et sur plasma. Résultats : Parmi les résultats notables, nous constatons que la plombémie médiane est divisée par deux, alors que les dosages ont été réalisés dans les mêmes conditions analytiques dans une cohorte similaire à celle analysée en 2003 (12,5 µg/L versus 26,3 µg/L -p < 0,0001). Une concentration sanguine plus élevée de cadmium est mesurée chez les fumeurs par rapport aux non fumeurs (1,18 µg/L versus 0,27 µg/L -p < 0,0001). Aucun métal et en particulier le mercure sanguin ou plasmatique n'est significativement augmenté chez les porteurs d'amalgames. Conclusion : Au cours des dix dernières années la plombémie médiane a été divisée par deux. S'agissant du métal le plus fréquemment surveillé en biologie clinique et en raison des concentrations mesurées, les dosages de plomb en routine devraient désormais être réalisés par ICP-MS. Mots clés : ICP-MS, métaux, plomb, sang, plasmaAbstract -Objective: Ten years after determining the normal concentrations in whole blood and plasma of approximately thirty elements by inductively coupled plasma mass spectrometry, it seemed useful to assess the impact of any changes in our environment on these values. Methods: One hundred and six healthy hospital staff volunteers of both sexes, without professional exposure to metals, not treated with lithium or strontium, taking no trace element or vitamin supplements, and without metallic prostheses, were included. Tobacco consumption and the number of dental amalgams were reported. A multi-elementary quantification of 26 metals (Li, Be, V, Cr, Mn, Co, Ni, Cu, Zn, As, Se, Rb, Sr, Mo, Ag, Cd, Sn, Te, Ba, W, Pt, Hg, TI, Pb, Bi and U) in whole blood and plasma was carried out by ICP-MS. Results: The median blood lead level is halved, while the assays were performed under the same conditions (12.5 µg/L versus 26.3 µg/L -p < 0.0001). The whole blood cadmium concentration is significantly higher in smokers compared with non-smokers (1.18 µg/L versus 0.27 µg/L -p < 0.0001). No metal, and in particular whole blood or plasma mercury, is significantly increased in subjects with amalgams. Conclusion: During this ten-year period, the median blood lead level was halved. D...

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“…Le dosage du mercure plasmatique a éga-lement été proposé comme marqueur biologique du mercure issu des amalgames dentaires [6]. S'il existe une corrélation positive entre le nombre d'amalgames et le mercure plasmatique, comme cela a été montré dans plusieurs études [6], le mercure inorganique plasmatique n'augmente en moyenne que de 0,02 μg/L par surface d'amalgame [7], ce qui est insignifiant.…”

Section: Applicationsunclassified

Dosage du mercure plasmatique par ICP-MS. Concentrations usuelles chez 53 sujets volontaires

et al. 2008

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Methylmercury and Inorganic Mercury in Serum—Correlation to Fish Consumption and Dental Amalgam in a Cohort of Women Born in 1922

Cited by 44 publications

References 14 publications

Dioxins, polychlorinated biphenyls, methyl mercury and omega-3 polyunsaturated fatty acids as biomarkers of fish consumption

Dioxins, polychlorinated biphenyls, methyl mercury and omega-3 polyunsaturated fatty acids as biomarkers of fish consumption

Profil métallique sanguin chez des volontaires sains : 10 ans après

Dosage du mercure plasmatique par ICP-MS. Concentrations usuelles chez 53 sujets volontaires

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