“…This study assessed the effect of P. acnes -killed on the concentration of TNF-α in the peritoneal cavity 6 h after CLP and there was a significant reduction in levels of this marker. Similar results were found in peritoneal fluid by Pang et al 38 that evaluated the modulating effect of the methylene chloride in animals with sepsis and reported a decrease in TNF-α and consequent increase in survival. Another study found that the decrease in concentration of TNF-α in serum and peritoneal exudate of animals treated with myrrh, an essential oil obtained from species of the genus Commiphora, increased survival in severe sepsis.…”