Methyl methacrylate and acrylamide crosslinked macroporous copolymers

Abstract

ABSTRACT:In this work the synthesis of a crosslinked macroporous copolymer was effected from methyl methacrylate and acrylamide. The synthesis process began with emulsion prepolymerization, followed by sol-gel copolymerization until a hard block was obtained. Determination of the properties of the obtained material was carried out by FTIR, mercury porosimetry, and SEM microscopy. The material was characterized by a porous structure with open pores. The macroporous copolymer obtained can be used for polymer-analog reactions and the transformation of amide and ester groups into acyl azide groups. It can be used as a hard inert support for the immobilization of enzymes, or other proteins, by condensation of acyl azide group on polymer with the free amino group from the base amino acid of enzyme/protein. For the immobilization of microorganisms it can be used by vacuum diffusion of microorganism suspension into the porous structure, without active group transformation reactions. With microorganisms in the polymer pores, microorganism colonies form within the copolymer by microbial fermentation.

Effect of Milling on Physicochemical Properties of Usnic Acid Isolated from Usnea sp.

“…Studies have been conducted in order to increase solubility usnic acid included using Poly Lactic-co-Glycolic Acid (PLGA) by preparing microencapsulation which the solubility enhance 21 fold 9 and forming inclusion complex with β−cyclodextrine that enhance usnic acid solubility about 23 fold 10 . Another method that can enhance the solubility is by milling method.…”

Deductive search for logic puzzles

“…The Nikoli challenges were taken from the Nikoli books Hashiwokakero 1 [20] and Hashiwokakero 2 [21] and the Times examples from the The Times book of Japanese Logic Puzzles [2].…”

“…Hashiwokakero is a Japanese logic puzzle from Nikoli [20], [21] in which the player must join hints in a square grid G to form a single connected set, using only horizontal and vertical edges. The cardinality of each vertex must equal its hint value, edges cannot cross, and no more than two edges can connect any pair of vertices.…”

Zig-Zag Numberlink is NP-Complete

“…Nikoli in fact publishes an entire range of such puzzles, following rules of their own and others' inventions; see Ref. [23]. The meta-puzzle for us theoretical computer scientists is to study the computational complexity of puzzles, characterizing them as polynomially solvable, NP-complete, or harder [7].…”