Methoxychlor in Chicken Breeder Diets

Lillie, Robert J.; Cecil, Helene C.; Bitman, Joel

doi:10.3382/ps.0521134

Cited by 6 publications

(3 citation statements)

References 6 publications

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“…Feeding of 25 to 5000 ppm methoxychlor, a pesticide whose use has increased since the banning of DDT, had no effect on shell thickness in laying hens (113). Similar results have been obtained for lindane at a concentration of 100 ppm (114).…”

Section: Other Pesticidessupporting

confidence: 61%

Effects of Chemicals on Egg Shell Formation

Mueller¹,

Leach²

1974

Annu. Rev. Pharmacol.

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Section: Other Pesticidessupporting

confidence: 61%

Effects of Chemicals on Egg Shell Formation

Mueller¹,

Leach²

1974

Annu. Rev. Pharmacol.

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“…METHOXYCHLOR Lillie et al (1973), Olney et al (1962), and Thompson et al (1967) detected minute amounts of methoxychlor in eggs and fat after feeding on high levels. Waldron and Naber (1974) and Onley et al (1975) did not detect any a n.m. = not measurable.…”

Section: Endrinmentioning

confidence: 98%

Accumulation of organochlorine pesticides in poultry: a review

Kan¹

1978

J. Agric. Food Chem.

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Accumulation ratios (level of pesticide in fat or egg to its level in the feed) of hexachlorobenzene (HCB),•, ß-, and 7-hexachlorocyclohexane (HCH), heptachlor and its epoxide, DDT, dieldrin, aldrin, endrin, and methoxychlor in laying hens and broilers are discussed. The pesticides can be grouped into several categories according to accumulation ratios: highly accumulating like HCB, d-HCH, heptachlor epoxide, dieldrin, aldrin; intermediate like heptachlor, endrin; low like a-and 7-HCH; and very low like methoxychlor. Depletion of residues of the pesticides in laying hens and eggs is correlated with the accumulative properties. Depletion of residues in broilers is mostly governed by growth rate and thus by dilution in the fat.

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“…There is also a recent report that embryonic exposure of male Japanese quail to very high concentrations of methoxychlor reduced sexual motivation (greatly increased latency to mount) at three months of age despite no obvious changes in reproductive variables such as testis weight (Eroschenko et al, 2002). Feeding methoxychlor to adult chickens did not in¯uence egg production, egg fertility, or male fertility (Lillie et al, 1973). Although these results suggest that methoxychlor acts on the HPG axis during development, speci®c endocrine measurements that address this possibility have not been made.…”

Section: Pesticides (Fungicides Herbicides and Insecticides)mentioning

confidence: 88%

Avian Models for Research in Toxicology and Endocrine Disruption

Scanes¹,

McNabb²

2003

Avian & Poul. Biolog. Rev.

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There have been significant strides in our knowledge of the effects of toxicants on birds. This communication presents a brief review of avian toxicology with emphasis on effects of common toxicants that disrupt endocrine system function and control of reproduction, growth, development, stress and calcium-phosphorus homeostasis. For those hormonal systems that act through hypothalamic-pituitary axes, we emphasize current knowledge of the axis``level'' at which the toxicants alter endocrine control. The classes of toxicants discussed are acid rain andyor aluminum, organochlorines such as polychlorinated biphenyls (PCBs), fungicides and insecticides, mycotoxins, (PCBs) and petroleum. The use of several types of avian models for endocrine disruption studies is discussed in the context of utility and practicality, developmental modes, species sensitivity and the choice of sentinel species. Promising new approaches for avian toxicological research are considered including shell-less embryos, continuous-flow administration of toxicants to avian embryos, gene microarrays, proteomics and metabolomics.

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Methoxychlor in Chicken Breeder Diets

Cited by 6 publications

References 6 publications

Effects of Chemicals on Egg Shell Formation

Effects of Chemicals on Egg Shell Formation

Accumulation of organochlorine pesticides in poultry: a review

Avian Models for Research in Toxicology and Endocrine Disruption

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