Methoxybifurcarenone: an antifungal and antibacterial meroditerpenoid from the brown alga Cystoseira tamariscifolia

Bennamara, A.; Abourriche, A.; Berrada, Mohamed Saleh; Charrouf, M.; Chaib, N.; Boudouma, Mohammed; Garneau, François-Xavier

doi:10.1016/s0031-9422(99)00040-0

Cited by 69 publications

(40 citation statements)

References 7 publications

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“…Furthermore, methoxybifurcarenone, isolated from the brown alga Cystoseira tamariscifolia, displayed an interesting antifungal activity toward various tomato pathogenic fungi including F. oxysperium f. sp. lycopersici [36]. Chbani et al [30] found that P. digitatum growth was not affected when treated by 200 mg/mL of S. vulgare dichloromethanol extract.…”

Section: Discussionmentioning

confidence: 99%

Control of Fusarium Dry Rot Incited by Fusarium oxysporum f. sp. tuberosi Using Sargassum vulgare Aqueous and Organic Extracts

Ammar¹,

Nefzi²,

Jabnoun‐Khiareddine³

et al. 2017

J Microb Biochem Technol

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Section: Discussionmentioning

confidence: 99%

Control of Fusarium Dry Rot Incited by Fusarium oxysporum f. sp. tuberosi Using Sargassum vulgare Aqueous and Organic Extracts

Ammar¹,

Nefzi²,

Jabnoun‐Khiareddine³

et al. 2017

J Microb Biochem Technol

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“…The extracts studied were obtained from retail and various algae were studied by the authors. Bennamara et al (1999) tried a purified compound from brown algae, methoxybifurcarenone, on bacteria and moulds and they found an antimicrobial activity on moulds only. The purified component is a minor component of the fatty components in the algae.…”

Section: Discussionmentioning

confidence: 99%

“…The second argument is more tangible. Some authors (Bennamara et al, 1999) had demonstrated an antimicrobial compound called methoxybifurcaremore but the authors had used a concentration procedure and purification of the pure compounds.…”

Section: Growth Inhibitionmentioning

confidence: 99%

“…In Morocco, the species Cystoseira tamaricifolia is widespread in the Atlantic Ocean coast between Tanger and Eljadida. Little is known about this species including studies carried out on the chemical aspect (Bennamara et al, 1999;Daoudi et al, 2001 Several works have been carried out on extracts from marine algae. Antimicrobial activities on bacteria and fungi were reported by Hellio et al (2000).…”

Section: Introductionmentioning

confidence: 99%

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Inhibition of growth and mycotoxins formation in moulds by marine algae Cystoseira tamariscifolia

Souhaili

Lagzouli

Faïd

et al. 2004

Afr. J. Biotechnol.

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Different extracts from marine algae (Cystoseira tamaricifolia) were tested for their antimicrobial activities. These extracts were examined for their activities on growth of moulds and yeasts and mycotoxines formation by moulds. The Minimal Inhibitory Concentration (MIC) was determined in every case in terms of dilutions. A total inhibition (100%) was obtained with the ethanolic crude extract on all the fungal species at the concentration of 10%. The aqueous extract showed an activity only on some strains used while no activity was observed on yeasts and moulds for both methanolic and aqueous extract. The other extracts (chloroform, hexane and methanol) had no activity on the microbial growth. Mycotoxins formation in Aspergillus flavus was inhibited by the ethanolic extracts at the concentration of 5%.

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“…Screening of algal extracts for biologically active compounds began in the 1950s with simple antibiotic assays and expanded to include testing for products with antiviral, antibacterial, antifungal, anti-mitotic, and antitumorigenic activities (16)(17)(18)(19). Studies on the antitumor effects of algal species have been reported by a number of researchers (20)(21)(22)(23).…”

Section: Introductionmentioning

confidence: 99%

Codium fragile Ethanol Extraction Inhibited Inflammatory Response through the Inhibition of JNK Phosphorylation

Han

Kim²,

Lee³

et al. 2010

JFN

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Codium fragile (CF) is an edible green alga consumed as a traditional food source in Korea. In this study, the ethanol extract of CF was evaluated to determine if it has anti-inflammatory activity. Lipopolysaccharide (LPS), a toxin from bacteria, is a potent inducer of inflammatory cytokines, such as tumor necrosis factor (TNF)-α and interleukin (IL)-6. Therefore, we studied whether CF extracts have an anti-inflammatory effect in LPS-induced murine macrophage cell lines (RAW 264.7). In the present study, IL-6 production was measured using an enzymelinked immunosorbent assay (ELISA), prostaglandin E 2 (PGE 2 ) production was measured using the EIA kit, and cyclooxygenase (COX)-2 and mitogen-activated protein kinase (MAPK) activation were determined by Western blot analysis. IL-6 mRNA, COX-2 mRNA and iNOS mRNA expression were measured using reverse transcriptionpolymerase chain reaction (RT-PCR). The results indicated that CF extracts inhibit LPS-induced IL-6, NO and PGE 2 production in a dose-dependent manner, as well as expression of iNOS and COX-2. CF extracts significantly inhibited LPS-induced c-Jun N-terminal kinase (JNK) 1/2 phosphorylation. Taken together, these findings may help elucidate the mechanism by which CF modulates RAW 264.7 cell activation under inflammatory conditions.

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Methoxybifurcarenone: an antifungal and antibacterial meroditerpenoid from the brown alga Cystoseira tamariscifolia

Cited by 69 publications

References 7 publications

Control of Fusarium Dry Rot Incited by Fusarium oxysporum f. sp. tuberosi Using Sargassum vulgare Aqueous and Organic Extracts

Control of Fusarium Dry Rot Incited by Fusarium oxysporum f. sp. tuberosi Using Sargassum vulgare Aqueous and Organic Extracts

Inhibition of growth and mycotoxins formation in moulds by marine algae Cystoseira tamariscifolia

Codium fragile Ethanol Extraction Inhibited Inflammatory Response through the Inhibition of JNK Phosphorylation

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