Methods for Insulin Delivery and Glucose Monitoring in Diabetes: Summary of a Comparative Effectiveness Review

Abstract

, before training in internal medicine and endocrinology and metabolism at the Johns Hopkins Hospital. During her fellowship in endocrinology, she received a master of health science degree in clinical epidemiology from the Johns Hopkins University Bloomberg School of Public Health. Her primary research interest centers around identifying endocrine risk factors associated with the development of diabetes and cardiovascular disease through the incorporation of measures of hormonal function into the design of clinical trials of cardiovascular risk modification, observational studies of incident cardiovascular disease and diabetes, and studies evaluating diabetic complications. Her current research focuses on studying the neuroendocrine response to chronic psychological stress as a risk factor for diabetes and cardiovascular disease. Dr Supplement Policy Statement Standards for Supplements to the Journal of Managed Care PharmacySupplements to the Journal of Managed Care Pharmacy are intended to support medical education and research in areas of clinical practice, health care quality improvement, or efficient administration and delivery of health benefits. The following standards are applied to all JMCP supplements to ensure quality and assist readers in evaluating potential bias and determining alternate explanations for findings and results. 1. Disclose the principal sources of funding in a manner that permits easy recognition by the reader. 2. Disclose the existence of all potential conflicts of interest among supplement contributors, including financial or personal bias. 3. Describe all drugs by generic name unless the use of the brand name is necessary to reduce the opportunity for confusion among readers. 4. Identify any off-label (unapproved) use by drug name and specific off-label indication. 5. Strive to report subjects of current interest to managed care pharmacists and other managed care professionals. S15 References Target AudiencesThis CME activity is designed to meet the educational needs of physicians, pharmacists, nurses, and case managers involved in the management and care of patients with diabetes. Learning ObjectivesBased on the findings from the Agency for Healthcare Research and Quality' s (AHRQ) comparative effectiveness review of insulin delivery and glucose-monitoring modalities for diabetes, participants should be able to: 1. Compare the benefits of insulin delivery systems in improving clinical outcomes, glycemic control, hypoglycemia, and quality of life in diabetic patients receiving intensive insulin therapy 2. Evaluate the differential effect of glucose-monitoring approaches on the process measures and intermediate and clinical outcomes in diabetic patients receiving intensive insulin therapy 3. Apply the AHRQ findings to guide effective, patient-centered clinical decisions Funding There is no fee for this CME/CE activity. This learning activity was prepared and funded under contract HHSA290201000006G from the Agency for Healthcare Research and Quality (AHRQ), U.S. Department of Hea...

Improving the Clinical Value and Utility of CGM Systems: Issues and Recommendations

“…A number of formal summaries of the CGM literature have been conducted (25)(26)(27)(28)(29)(30)(31)(32). Although this suggests that the field is coming of age, review of the existing evidence base has generated diverse conclusions, ranging from "limited evidence" (Cochrane review) (25) to fully supportive (28)(29)(30).…”

De la bomba de insulina y el monitoreo continuo de glucosa al páncreas artificial

“…La mayor reducción se ha visto con SAPT en pacientes con DM1 (-0,68%) [22][23] . Si bien la mejoría en el control metabólico parece discreta, esto se debe analizar en el contexto que los pacientes enrolados en estos estudios tienen en general un buen control metabólico al ingreso del estudio.…”

“…Diferentes estudios muestran un impacto positivo sobre la calidad de vida de los usuarios de ICSI o SAPT comparado con MDI [22][23] , siendo infrecuente que los pacientes decidan suspender el uso de este tipo de dispositivos y volver a MDI (2-11%) [31][32] .…”

Russian national guidelines on insulin pump therapy and continuous glucose monitoring for diabetes mellitus patients. DRAFT

“…Метаболические и психосоциальные • НМГ-РВ улучшает контроль гликемии (Класс I; Уровень А) [51][52][53][54][55].…”