2015
DOI: 10.30809/phe.1.2015.39
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Methodological basics of effectiveness analysis of health technologies in pharmacoeconomic studies

Abstract: The article presents the methodological basics of the effectiveness analysis in pharmacoeconomic studies of medicinal drugs or health technologies. In particular, the main challenge that researchers face is the defining criterion of the effectiveness of the evaluated alternatives is described. What is more, main positive and negative sides of using surrogate and final performance criteria, as well as provide methodological recommendations for their selection and evaluation.

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Cited by 7 publications
(7 citation statements)
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“…The first stage of this pharmacoeconomic study included a retrospective analysis of clinical effectiveness which included of selection of criterion of effectiveness and search for effectiveness values relevant for the RRT types under study [19]. Relevant foreign publications were searched in the database PubMed, Medlink, Cochrane, and Russian-language publications -in the database "Russian Medicine" of the Central Medical Research Library of the I.M.…”
Section: Methodsmentioning
confidence: 99%
“…The first stage of this pharmacoeconomic study included a retrospective analysis of clinical effectiveness which included of selection of criterion of effectiveness and search for effectiveness values relevant for the RRT types under study [19]. Relevant foreign publications were searched in the database PubMed, Medlink, Cochrane, and Russian-language publications -in the database "Russian Medicine" of the Central Medical Research Library of the I.M.…”
Section: Methodsmentioning
confidence: 99%
“…That is why the rate of progression-free survival (PFS) was selected in the analysis of «cost-effectiveness» in this study as the criterion of effectiveness [21,22,23].…”
Section: Methodsmentioning
confidence: 99%
“…By the time of enrollment to the trial the evidence of neurological deficit in both groups was virtually the same (NIHSS score 9-10, Rankin scale score 3-4, Rivermead mobility index 6-7). By the end of hospitalization (on the [15][16] th day) NIHSS score in the basic group decreased from 9-10 to 2-5, Rankin score from 3-4 to 1-2, Rivermead mobility index Rivermid changed from 6 7 to 9-14. In the control group the neurological deficit varied much less.…”
Section: Introductionmentioning
confidence: 99%