Methodological aspects of ensuring and improving diagnostic effectiveness of quantitative immunochemiluminescent studies. Model of ‘clinical uncertainty’ as part of laboratory modules of clinical recommendations and educational programs

Abstract

Technological capabilities make it possible to increase the diagnostic efficiency of quantitative immunochemiluminescent studies but require expanding the glossary of the clinical and laboratory consultation, taking into account metrological approaches to quality assurance. The variants of quantitative assessment of the “clinical uncertainty of assessing the patient’s condition based on a laboratory test”, formed taking into account the models of analytical quality requirements, are proposed. The clinical significance of the introduction of metrological approaches to ensuring and expressing accuracy in the practice of quantitative immunochemiluminescent studies in order to reduce risks and improve the safety of medical activities is demonstrated.