Methionine production by microorganisms

Abstract

Microbial production of methionine is reviewed with 73 references. The review describes different methionine-producing organisms, as well as analog-resistant regulatory mutants, their optimum cultural conditions and yields. The pathways of methionine biosynthesis and their regulation are discussed.

Optimization of Fermentation Conditions of <i>Bacillus thuringiensis</i> EC1 for Enhanced Methionine Production

“…The isolation of Bacillus organisms as methionine producers agrees with the works of other investigators [14]. However, Bacillus species are not yet known to be very active producers as species of Corynebacterium, Brevibacterium and Arthrobacter [8] [15].…”

Volatile Sulfur Compounds Produced by Helicobacter pylori

“…21 A variety of microorganisms that produce methionine were reviewed in putting forth this metabolic hypothesis. 31 On the basis of the above pathway, one can argue that with an abundance of cysteine, this strain can metabolize cysteine, and by using cysteine and hydrogen sulfide, it can produce methionine. Although this hypothesis warrants further debate, it is consistent with several findings of this study.…”

Involvement of BcStr2 in methionine biosynthesis, vegetative differentiation, multiple stress tolerance and virulence in Botrytis cinerea

“…Methionine (Met) is a crucial sulfur-containing amino acid. Apart from its role as a protein constituent and its central role in the initiation of mRNA translation, Met serves as the main methyl donor for various cellular processes by acting as the intermediary of S-adenosylmethionine (SAM) (Mondal et al, 1996). SAM is the primary biological methyl group donor for a number of essential cellular processes, including DNA methylation, cell division, cell wall biosynthesis and chlorophyll biosynthesis (Roje, 2006).…”