Methanol Extract of Three Medicinal Plants from Samburu in Northern Kenya Show Significant Antimycobacterial, Antibacterial and Antifungal Properties

Marita, R.M.; Ogol, C. K. P. O.; Oguge, Nicholas; Okemo, P. O.

doi:10.3923/rjmp.2011.54.64

Cited by 33 publications

(27 citation statements)

References 8 publications

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“…Commiphora myrrha (Burseraceae) has important terpenoids, which are the characteristic constituents of this plant species (Su et al, 2009), and sesquiterpenes, which show neuroprotective effects (Xu et al, 2012). Scadoxus multiflorus is also a medicinal plant and its extract has antimycobacterial, antibacterial and antifungal properties (Mariita et al, 2011). All these plant species are rare in the Kingdom of Saudi Arabia and have small population sizes; therefore, their molecular characterization and phylogenetic study are necessary.…”

Section: Introductionmentioning

confidence: 99%

Assessment of phylogenetic relationship of rare plant species collected from Saudi Arabia using internal transcribed spacer sequences of nuclear ribosomal DNA

Al‐Qurainy¹,

Khan²,

Nadeem³

et al. 2013

Genet. Mol. Res.

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ABSTRACT.The rare and endangered plants of any country are important genetic resources that often require urgent conservation measures. Assessment of phylogenetic relationships and evaluation of genetic diversity is very important prior to implementation of conservation strategies for saving rare and endangered plant species. We used internal transcribed spacer sequences of nuclear ribosomal DNA for the evaluation of sequence identity from the available taxa in the GenBank database by using the Basic Local Alignment Search Tool (BLAST). Two rare plant species viz, Heliotropium strigosum claded with H. pilosum (98% branch support) and Pancratium tortuosum claded with P. tenuifolium (61% branch support) clearly. However, some species, viz Scadoxus multiflorus, Commiphora myrrha and Senecio hadiensis showed close relationships with more than one species. We conclude that nuclear ribosomal internal transcribed spacer sequences are useful markers for phylogenetic study of these rare plant species in Saudi Arabia.

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Section: Introductionmentioning

confidence: 99%

Assessment of phylogenetic relationship of rare plant species collected from Saudi Arabia using internal transcribed spacer sequences of nuclear ribosomal DNA

Al‐Qurainy¹,

Khan²,

Nadeem³

et al. 2013

Genet. Mol. Res.

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“…Their role is to protect plants against microbial or insect damage [23]. Since medicinal plants contain pharmacologically active substances with antimycobacterial, antibacterial and antifungal properties [24], the antibacterial activity of the plants tested could therefore be attributed to the presence of these compounds.…”

Section: Discussionmentioning

confidence: 99%

Anti-nociceptive properties in rodents and the possibility of using polyphenol-rich fractions from sida urens L. (Malvaceae) against of dental caries bacteria

Konaté¹,

Zerbo

Ouédraogo

et al. 2013

Annals of Clinical Microbiology and Antimicrobials

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BackgroundSida urens L. (Malvaceae) is in flora of Asian medicinal herbs and used traditionally in West of Burkina Faso for the treatment of infectious diseases and particularly used against, dental caries bacteria, fever, pain and possesses analgesic properties. This study was conducted to reveal the antibacterial effect against dental caries bacteria on the one hand, and evaluate their analgesic capacity in experimental model with Swiss mice and on the other hand, with an aim to provide a scientific basis for the traditional use of this plant for the management of dental caries bacteria.MethodThe antibacterial assays in this study were performed by using inhibition zone diameters, MIC (Minimum inhibitory concentration) and MBC (Minimal bactericidal concentration) methods. On the whole the dental caries bacteria (Gram-positive and Gram-negative bacterial strains) were used. Negative control was prepared using discs impregnated with 10% DMSO in water and commercially available Gentamicin from Alkom Laboratories LTD was used as positive reference standards for all bacterial strains. In acute toxicity test, mice received doses of extract (acetone/water extract) from Sida urens L. by intraperitoneal route and LD50 was determined in Swiss mice. As for analgesic effects, acetic acid writhing method was used in mice. The acetic acid-induced writhing method was used in mice with aim to study analgesic effects.ResultsThe results showed that the highest antibacterial activities were founded with the polyphenol-rich fractions against all bacterial strains compared to the standard antibiotic. About preliminary study in acute toxicity test, LD50 value obtained was more than 5000 mg/kg b.w. Polyphenol-rich fractions produced significant analgesic effects in acetic acid-induced writhing method and in a dose-dependent inhibition was observed.ConclusionThese results validate the ethno-botanical use of Sida urens L. (Malvaceae) and demonstrate the potential of this herbaceous as a potential antibacterial agent of dental caries that could be effectively used for future health care purposes.

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“…A few drops of 0.1% ferric chloride was added and observed for brownish green or a blue-black coloration [30].…”

Section: Test For Tanninsmentioning

confidence: 99%

“…The froth was mixed with 3 drops of olive oil and shaken vigorously, then observed for the formation of emulsion [30].…”

Section: Test For Saponinsmentioning

confidence: 99%

In-Vitro Anthelmintic Bioactivity Study Of Eclipta prostrata L. (Whole Plant) Using Adult Haemonchus contortus worms A Case Study Of Migori County, Kenya

Sirama¹,

Kokwaro²,

Owuor³

et al. 2014

IOSRJPBS

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Methanol Extract of Three Medicinal Plants from Samburu in Northern Kenya Show Significant Antimycobacterial, Antibacterial and Antifungal Properties

Cited by 33 publications

References 8 publications

Assessment of phylogenetic relationship of rare plant species collected from Saudi Arabia using internal transcribed spacer sequences of nuclear ribosomal DNA

Assessment of phylogenetic relationship of rare plant species collected from Saudi Arabia using internal transcribed spacer sequences of nuclear ribosomal DNA

Anti-nociceptive properties in rodents and the possibility of using polyphenol-rich fractions from sida urens L. (Malvaceae) against of dental caries bacteria

In-Vitro Anthelmintic Bioactivity Study Of Eclipta prostrata L. (Whole Plant) Using Adult Haemonchus contortus worms A Case Study Of Migori County, Kenya

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