Methadone, methadone treatment and non-fatal overdose

Neale, Joanne

doi:10.1016/s0376-8716(99)00070-8

Cited by 28 publications

(13 citation statements)

References 28 publications

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“…However, heroin purity and overdose fatalities have been found to be moderately related, with deaths more likely to be the result of combining heroin with other depressant drugs [13,15]. A large number of drug users attributed their overdoses to polydrug use and low tolerance, and a minority to suicidal intentions, confirming previously reported findings of the risk factors for overdose [2,10] and demonstrating awareness among drug users of the most common causes of overdoses. The findings suggest that the majority of the current sample had overdosed as a result of combinations of drugs.…”

Section: Discussionsupporting

confidence: 79%

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Relationship between Prescribing and Risk of Opiate Overdose among Drug Users in and out of Maintenance Treatment

Man¹,

Best²,

Gossop³

et al. 2003

Eur Addict Res

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Opiate users (n = 135) from southern England, Glasgow and Edinburgh were interviewed about opiate overdose (lifetime). Fifty-six percent had overdosed. The majority (66%) reported mixing opiates with at least one other drug (mainly alcohol and/or benzodiazepines) at their last overdose. Patients identified misjudgements of purity, mixing drugs and misjudgements of tolerance as causes of overdose. The sample was divided into groups: (1) ‘no prescription’, (2) prescribed ‘diazepam only’, (3) prescribed ‘methadone only’ and (4) prescribed ‘methadone + diazepam’. The ‘methadone + diazepam’ group reported more lifetime and deliberate overdoses, the ‘methadone only’ group were more likely to have used several drugs at the time of their last overdose and the ‘no prescription’ group to have used only heroin. Drug users’ overdose risk may vary as a result of their prescribed and non-prescribed drug use. Interventions should be developed and tailored according to clients’ needs and current use patterns.

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Section: Discussionsupporting

confidence: 79%

“…There are several risk factors for overdose including route of drug administration [8,9], reduced tolerance [10,11] and suicidal intention [6,10]. However, the most commonly identified risk factors for overdose are concurrent alcohol and poly-drug use.…”

Section: Introductionmentioning

confidence: 99%

Relationship between Prescribing and Risk of Opiate Overdose among Drug Users in and out of Maintenance Treatment

Man¹,

Best²,

Gossop³

et al. 2003

Eur Addict Res

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show abstract

“…IC has its origins in a study of non‐fatal overdose conducted by the current author in 1997–99 28, 29, 30, 31. This involved 200 qualitative interviews transcribed verbatim (‘denaturalized transcription’) by professional transcribers plus observational data.…”

Section: Iterative Categorizationmentioning

confidence: 99%

Iterative categorization (IC): a systematic technique for analysing qualitative data

2016

Self Cite

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The processes of analysing qualitative data, particularly the stage between coding and publication, are often vague and/or poorly explained within addiction science and research more broadly. A simple but rigorous and transparent technique for analysing qualitative textual data, developed within the field of addiction, is described. The technique, iterative categorization (IC), is suitable for use with inductive and deductive codes and can support a range of common analytical approaches, e.g. thematic analysis, Framework, constant comparison, analytical induction, content analysis, conversational analysis, discourse analysis, interpretative phenomenological analysis and narrative analysis. Once the data have been coded, the only software required is a standard word processing package. Worked examples are provided.

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“…The number of individuals reported to have lived with friends was 28 (6.5%) which was a proportional decrease from 2010 (10.6%). The proportions of those living in a hostel (23,5.3%), homeless accommodation (13, 3%) and/or with no fixed abode/sleeping rough (26, 6%) were similar to 2010 (4.9%, 1.1%, 4% respectively).…”

Section: Living Arrangementsmentioning

confidence: 86%

“…A dose that is too high can lead to an overdose, however a dose that is too low can lead to withdrawal which can lead to individuals "topping up" with other drugs such as illicit opiates and benzodiazepines [22]. Similarly there is evidence to suggest that individuals who wish to begin a methadone prescription but who have been unsuccessful in their efforts to achieve this are at a risk of overdose [23]. Therefore further investigation concerning the role of dose and not being on a methadone prescription in methadoneimplicated deaths is required.…”

Section: Toxicology and Substitute Prescribingmentioning

confidence: 99%

Lets chew up the evidence – A comment on the prohibition of khat

2013

Drugs and Alcohol Today

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Methadone, methadone treatment and non-fatal overdose

Cited by 28 publications

References 28 publications

Relationship between Prescribing and Risk of Opiate Overdose among Drug Users in and out of Maintenance Treatment

Relationship between Prescribing and Risk of Opiate Overdose among Drug Users in and out of Maintenance Treatment

Iterative categorization (IC): a systematic technique for analysing qualitative data

Lets chew up the evidence – A comment on the prohibition of khat

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