Metastatic involvement of parotid from carcinoma of the breast—a case report

Abstract

Microscopic examination of parotid and breast revealed that parotid gland was involved as a distant metastases from a breast carcinoma, indicating that a swelling in the parotid needs to be assessed and investigated very carefully.

Synchronous isolated ipsilateral salivary gland metastasis from a primary breast cancer – A case report

“…[6,7] On the other hand, parotid metastatic disease originating from distant infraclavicular sites is rare; tumor cells from such sites are thought to reach the parotid gland through the thoracic duct or the paraspinal venous plexus. [8] The majority of parotid metastasis from breast cancer reported in the literature originate from invasive ductal carcinoma. [9] In 2000, Joyce et al reported the first documented case of breast cancer metastasizing to the parotid gland in a male patient.…”

“…For example, primary salivary duct carcinoma mainly affects elderly men, and its occurrence as a metachronous or synchronous tumor with ductal carcinoma of the breast is unlikely and rarely described in the literature. [8] When metastatic carcinoma is identified by parotid FNA biopsy, restaging with [18F]-fluorodeoxyglucose positron emission tomography-CT scan is recommended to evaluate locoregional and look for distant disease. [16] Treatment planning is then based on radiological staging.…”

Parotid Gland Metastasis of Breast Cancer: Case Report and Review of the Literature

“…Distant spread through the lymphatic route occurs to the mediastinal and supraclavicular lymph nodes. Also hematogenous spread occurs and leads to metastasis to lung, liver, bone, adrenals, and brain [10]. How- adjuvant chemotherapy [15].…”

“…Metastatic parotid gland involvement accounts for approximately 9-14% of all parotid tumors [1]. Metastasis to the parotid gland from breast cancer is extremely rare, and to our knowledge only 14 cases have been reported between 1982 and 2010 [2][3][4][5][6][7][8][9][10]. We report a case of invasive lobular carcinoma of the breast which spread to the parotid gland, and we summarize the 14 cases that have been reported.…”

“…In a review of autopsy studies which included 167 cases of breast cancer, only 1 case of metastasis to the parotid gland was detected [11]. Also, a search of the MEDLINE database (1982-2010) revealed merely 14 cases (table 1) [2][3][4][5][6][7][8][9][10]. One reason for the rarity of this event is the anatomical location.…”