Metastatic Angiosarcoma Presenting as Ischemic Anterior Circulation Stroke

Ramachandren, Thavenesh; Venkataraman, Karthik; Hussey, Keith; Ferguson, L.

doi:10.1016/j.avsg.2015.08.025

Cited by 2 publications

(2 citation statements)

References 11 publications

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“…Intimal sarcoma (IS) is a mesenchymal-derived malignancy of the great vessels rarely reported in the carotid artery. 1-4 This is a report of (1) carotid IS presenting as acute large vessel occlusion and (2) diagnosis of IS by cerebral arterial embolus histopathology post-thrombectomy with no identifiable primary site. Our patient was a male in his sixth decade with a history of schizoaffective disorder who presented 8 hours since last known well with right-sided weakness, right hemineglect manifesting with inattention, and dysarthria.…”

Section: Case Reportmentioning

confidence: 99%

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Carotid Intimal Sarcoma Presenting as Large Vessel Occlusion and Diagnosed by Embolus Histopathology

et al. 2023

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ObjectiveThe objective of this study was to present the clinical, histopathologic, and radiographic findings of a unique case of intimal sarcoma (IS) embolus presenting as a large vessel occlusion causing an ischemic stroke without a detectable primary tumor site.MethodsExtensive examinations, multimodal imaging, laboratory testing, and histopathologic analysis were used in evaluation.ResultsWe report the case of a patient who presented with acute embolic ischemic stroke and was found to have IS based on a histopathologic evaluation of his embolectomy specimen. Subsequent comprehensive imaging studies failed to detect a primary tumor site. Multidisciplinary interventions including a course of radiotherapy were performed. The patient died of recurrent multifocal strokes 92 days after diagnosis.DiscussionMeticulous histopathologic analysis should be conducted on cerebral embolectomy specimens. Histopathology may be useful in diagnosing IS.

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Section: Case Reportmentioning

confidence: 99%

“…In limited case reports, carotid IS typically presents with stuttering, progressive ischemia, and a painful neck mass. 1-3 The diagnosis has been performed using tissue obtained by fine needle aspiration 4 or en bloc resection 3 of expansile tumors.…”

Section: Case Reportmentioning

confidence: 99%