Metastasis of lung adenocarcinoma to the mandible: Report of a case

Abstract

Adenocarcinoma of the lung that metastasizes to the mandible is uncommon. There are only a few cases described in the English-language literature regarding metastasis to mandible from adenocarcinoma of the lung. This article shows a metastasis from adenocarcinoma of the lung affecting the mandible of a 55-year-old male patient where the metastatic lesion was detected before primary tumor. This article emphasizes the importance of detailed dentoalveolar examination and early diagnosis for finding the primary focus of metastatic lesions.

Metastatic adenocarcinoma of mandible: in search of the primary

“…Similar cases of unknown primary with a metastatic lesion in the mandible have been reported previously 4–10. Most common symptoms reported were swelling and altered sensation 3.…”

Unusual Presentation of an Adenocarcinoma of the Lung Metastasizing to the Mandible, Including Molecular Analysis and a Review of the Literature

“…Therefore, the assessment was done among 108 patients. Metastatic lung carcinoma was more prevalent in men (n: 86) versus women (n: 22), with a ratio of 3.90:1.…”

“…Lung carcinoma metastatic tumors in the oral cavity are a challenge to diagnose due to their rarity and the fact that they possess complex clinical characteristics identical to all metastatic tumors [1,14,22]. Most of the information is presented in isolated case reports or in small series of cases in reviews of metastatic disease in the jaw.…”

“…Twenty-four articles were identified from 1,482 publications [12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31]. The distribution of the 24 publications that entered the final review is as follows: case reports (n: 11), review data from a single institution (n: 11), review data from three institutions (n: 1), systematic reviews or data from multiple institutions (n: 1).…”

Maxillary metastasis from carcinoma lung: An unusual presentation

“…[1,2] Common sources of metastasis to oral region are breast, lung, and kidney. [3] These lesions can mimic dental infections and can hinder speech and nutrition. The case presented here was first symptomatic with facial swelling and then was detected to have metastatic lung cancer.…”