Metástasis cerebral de carcinoma urotelial de vejiga

Abraham, Marina Sanchez; Guagnini, Marcelo; Sousa, Leandro; Romano, Lucas Martín; Alemán, Alberto

doi:10.1016/j.neuarg.2011.02.002

Cited by 1 publication

(3 citation statements)

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“…According to current medical literature, the incidence of CNS evolvement of disseminated TCC varies from 0.6% -8%, [9][10][11] and bladder carcinoma accounts for 0.5% of all intracranial metastases. 8 Brain metastases as the first metastatic manifestation without evidence of recurrent or disseminated disease is extremely rare, with only few cases reported in the literature.…”

Section: Discussionmentioning

confidence: 99%

“…11,12,17,20 This theory is advocated by many authors who believe that aggressive chemotherapy (in a regimen including methotrexate, vinblastine, doxorubicin, and cisplatin) prolongs the duration of tumor remission but does not cross the blood-brain barrier. 4,11,20 In other words, the advent of the new chemotherapy regimen improved the primary and systemic control of the urinary bladder cancer, allowing patients to live long enough to develop cerebral metastasis. 13 According to Rabadán et al, the median time between TCC diagnosis and its metastasis is 12 to 18 months, and usually the patient has multiple organs involved, not only the CNS.…”

Section: Discussionmentioning

confidence: 99%

“…19,22 CNS metastases involve cerebral hemispheres in 80% of the cases, 5% in the brainstem and 15% in the cerebellum. 11 According to tumor localization, the patient may complain of regular and unspecific headache, or suddenly develop seizures, neurologic deficit, or behavioral changes. 21 Patients with cerebellar metastases often complain about occipital and/or frontal headaches and gait disturbances.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Cerebellar Single Metastases from Bladder Transitional Cell Carcinoma: A Case Report

et al. 2016

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Cerebral metastasis is the most common cancer in the Central Nervous System (CNS); however, the bladder is a rare primary origin. The incidence of bladder metastases to the brain tissue has slightly increased in the past decades, with a few case reports published in medical literature, but not in Brazil. The authors describe a case of a female with prior diagnosis and treatment of transitional cellular cancer, without signs or symptoms of local or disseminated relapse, who suddenly developed clinical signs of cerebellum impairment. The patient was submitted to neurosurgical procedure with good outcome, followed by oncologic adjuvant treatment.

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Section: Discussionmentioning

confidence: 99%