Metastases of Glomus Jugulare Tumors

Catecholamine secreting tumor of the glomus jugulare

“…N o association was found with a p h a c o m a t o s i s (e.g., yon H i p p e l -L a n d a u disease, S t u r g e -W e b e r disease, von Recklinghausen disease), as has been reported [18,41]; also was there no indication for a genetic or familial trait [33]. The tumor, while locally strongly invasive, has the aspects of a benign tumor, and a search for metastases was negative; the tumors can, however, be m a l i g n a n t and metastasize [9,35]. The first applied treatment, in 1967, was a partial resection of the t u m o r p r o t r u d i n g into the external a u d i t o r y canal.…”

Radiosurgery of Glomus Tumors: Midterm Results

“…Histologically, paragangliomas are benign and have rare mitotic activity. However, malignant transformation with metastatic spread into liver, lung and bone can be seen in 3% [1,2]. According to the origin, they are called glomus tympanicum tumors (middle ear cleft), glomus jugulare tumors (jugular bulb) or glomus vagale tumors (posterior part of the jugular foramen).…”

“…They are also called paragangliomas or chemodectomas. The incidence of malignant transformation is between 2% and 3% [1,2].…”

Multiple Sclerosis After X-radiation: Activation by Treatment of Metastatic Glomus Tumor

“…The reported incidence of metas¬ tasis among these tumors is less than 4%,4 and only ten cases of metastatic glomus jugulare tumor were found in the literature. 1 …”