Métastases gastriques et duodénales de cancer du rein à cellules conventionnelles

Haffner, Jérémie; Morel, Jean-François; Maunoury, V.; Caty, Armelle; Biserte, J; Villers, Arnauld

doi:10.1016/s1166-7087(07)78566-4

Cited by 9 publications

(5 citation statements)

References 14 publications

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“…[ 5 ] detected five new cases among 2,082 patients with RCC (0.2%). The mean (median, range) time to diagnosis of gastric metastases in the present case and those reported previously was 6 (4.7, 0.1 to 20) years; other studies showed even later appearance: 6.6 years (range: 2 years to 14 years) [ 7 ]. There are few studies (around 20) showing the association between gastric metastasis from RCC and other metastasis of the same tumor.…”

Section: Discussionsupporting

confidence: 58%

“…There are various types of treatment such as embolization, epinephrine injection or systemic therapy (for example, octreotide and sorafenib) [ 12 – 17 ]. Even in patients without curative approach, surgery could be the elective treatment [ 7 ]. However, there are many issues involving the surgical approach, such as mortality, morbidity, the size and number of the metastatic disease, and patient condition.…”

Section: Discussionmentioning

confidence: 99%

“…[ 11 ], chemotherapy in patients with unrecognized stomach metastases may result in tumor necrosis followed by perforation of the stomach and rapid death. The treatment options could be embolization, epinephrine injection, endoscopic resection or surgery [ 12 – 17 ], even in palliative patients [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

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Palliative laparoscopic resection of renal cell carcinoma metastatic to the stomach: report of a case

et al. 2014

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The most common sites of metastases in renal cell carcinoma (RCC) are lung and bone. However, unusual sites, including the stomach, are characteristic of RCC.This article presents a case of a metastatic RCC (lung and liver) with a symptomatic gastric metastasis treated by a laparoscopic wedge resection (LWR).A 66-year-old woman, diagnosed with RCC underwent a right nephrectomy. During her follow-up, an upper gastrointestinal (GI) endoscopy showed an ulcerated lesion at the stomach. A biopsy of the specimen revealed metastatic RCC. The patient underwent a palliative LWR and was discharged home 8 days after surgery.Therefore, LWR is a relatively simple technique with the advantages of minimal invasive access in the treatment of palliative cases.

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Section: Discussionsupporting

confidence: 58%

Section: Discussionmentioning

confidence: 99%

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Palliative laparoscopic resection of renal cell carcinoma metastatic to the stomach: report of a case

et al. 2014

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“…On the other hand, the diffuse type of gastric carcinoma is more prevalent in women and in individuals under the age of 50. Note that in a patient with a prior history of RCC, there are case studies illustrating that surveillance EGD can be performed in the setting of undiagnosed upper GI hemorrhage, as it may herald the recurrence of RCC [6]. …”

Section: Discussionmentioning

confidence: 99%

Metastatic Renal Cell Cancer and a Gastric Mass: An Unusual Finding

Senadhi

Jani²,

Erlich³

2010

Case Rep Gastroenterol

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Renal cell cancer (RCC) accounts for approximately 3% of all adult malignancies. RCC has a metastasis rate of approximately 25%, which is most commonly to the lungs (>50%). On the contrary, RCC metastasis to the gastrointestinal tract (excluding the liver) is very uncommon and ranges from 0.2 to 0.7%. Thus, a gastric cancer in a patient with known metastatic RCC would most likely be secondary to metastasis. We present the first reported case of a metastatic RCC coexisting with a new-onset primary gastric cancer and a review of management using guidelines from metastatic RCC to the stomach. An 82-year-old African American male with papillary RCC status post left nephrectomy with recurrence of liver metastasis presented with failure to thrive shortly after his third cycle of chemotherapy despite stable disease by imaging studies. He had received 7 chemotherapy cycles of Gemzar, Nexavar, and Avastin prior to admission. He subsequently had a drop in his hemoglobin and was found to have hemoccult positive stool in the setting of recent Avastin. Endoscopic evaluation showed a 3 cm ulcerated mass in the cardia which was biopsied. The biopsy showed invasive and poorly differentiated gastric adenocarcinoma unrelated to his RCC. The patient subsequently underwent partial gastrectomy with loop gastrojejunostomy for resection of his stage 1 primary gastric adenocarcioma. The surgery also facilitated future chemotherapy (Avastin), which could not be given prior to surgery due to its side effect of bleeding. The patient did not receive adjuvant chemoradiation for his gastric cancer due to his comorbidities at the time and was doing well at a one month follow-up. Metastatic RCC and primary gastric cancer can coexist, especially when there is an overlap of risk factors such as smoking or nitrosamines. The management of a gastric cancer in the setting of metastatic RCC is similar to the management of solitary primary gastric carcinoma. Treatment of the primary gastric cancer can facilitate future chemotherapy such as Avastin, which has been recently approved for the treatment of metastatic RCC.

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“…RCC has a propensity to metastasize to another organs, including bilateral adrenal glands [8], skin [9,10], pancreas and spleen [11], gastric or duodenal systems [12], skeleton [13], pancreas [14] and bladder [15,16]. However, metastases from RCC rarely affect the head and neck region [17].…”

Section: Case Presentationsmentioning

confidence: 99%

Metastatic renal cell carcinoma to the jaws: report of cases

2014

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Renal cell carcinoma (RCC) is one of the most frequent urological malignancies in adults. RCC often metastasizes to other organs, but rarely to the oromaxillofacial region. Metastatic tumors to the jaws are also unusual. In this report, we present two cases of RCC metastasis to the jaws. Metastatic RCC is resistant to radiotherapy and chemotherapy, so surgery is the primary therapeutic choice. This report describes the diagnostic procedures utilized and the therapeutic process in the two cases. The differential diagnosis and treatment methods are discussed.

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Métastases gastriques et duodénales de cancer du rein à cellules conventionnelles

Cited by 9 publications

References 14 publications

Palliative laparoscopic resection of renal cell carcinoma metastatic to the stomach: report of a case

Palliative laparoscopic resection of renal cell carcinoma metastatic to the stomach: report of a case

Metastatic Renal Cell Cancer and a Gastric Mass: An Unusual Finding

Metastatic renal cell carcinoma to the jaws: report of cases

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