“…In November 1902, the first report of an endocrine pancreatic tumor was published by the Canadian pathologist Albert George Nicholls (1870Nicholls ( -1946 1 . In September 1907, the German pathologist Siegfried Oberndorfer (1876Oberndorfer ( -1944 presented his observations on the nature of a morphologically distinct class of tumors which he referred to as carcinoids 2,3 , i.e., carcinoma-like neoplasms behaving like benign neoplasms. He thereby became the first to characterize neuroendocrine neoplasms (NENs).…”