In this study, the aim is to minimize interference between closely spaced micro strip patch antenna elements, and we achieved this by developing various techniques. The recent trends in wireless applications is one of multiple input multiple output design, which has increased the need for multiple antenna integration in the user's equipment. Without using additional power or frequency band, a MIMO antenna is utilized to increase the channel's capacity. It necessitates a large number of antennas configured in the transmitter with minimal connection. Statistical Therefore, low mutual coupling between the antennas is necessary for an effective MIMO antenna system. The paper examines numerous isolation methods put out in recent years. It includes a thorough investigation of design concerns like antenna downsizing, integration problems, antenna coupling, and isolation improvement methods.