Metallic nanocrystallites-incorporated ordered mesoporous carbon as labels for a sensitive simultaneous multianalyte electrochemical immunoassay

Fang, Yishan; Huang, Xinjian; Zeng, Qiang; Wang, Lishi

doi:10.1016/j.bios.2015.05.046

Cited by 23 publications

(7 citation statements)

References 51 publications

(48 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Biosensor type, employed bioreceptor, transducing procedure, and obtained limits of detection (LOD) for target drug are outlined. [67][68][69][70][71][72][73][74][75][76][77][78][79][80][81][82][83][84][85]…”

Section: Electrochemical Sensorsmentioning

confidence: 99%

Nanoarchitectonics for Abused‐Drug Biosensors

Moradi

Khalili

Septiani

et al. 2021

Small

View full text Add to dashboard Cite

analogs). Illicit drugs cause damaging lifetime alterations in the brain, making it very difficult to overcome the addiction without specialized, medical assistance. Drug addiction is a long-lasting, reverting psychiatric disorder and is a major public health issue affecting many elements in society such as health care, productivity, policing, crimes, and accidents. According to 2008 estimations, roughly, 4 million people are using opium globally and 80% of them are living in Asia. Studies have shown a link between opium use and diverse adverse health effects such as different types of cancers including oral, bladder, lung, and gastric cancers. [5][6][7] Opioid derivatives, morphine, codeine, fentanyl, or buprenorphine are effective analgesics for post-operative and cancer pain relief but several studies have highlighted the link between their long-term administration and high abuse potential. [8] Morphine is the most potent analgesic for chronic pain; however, its clinical use is restricted since the opiate naturally brings about tolerance and has severe withdrawal symptoms with a high risk of relapse. Over-the-counter Rapid, accessible, and highly accurate biosensors for the detection of addictive and abused drugs are needed to reduce the adverse personal and societal impacts of addiction. Modern sensors that utilize next-generation technologies, e.g., nanobiotechnology and nanoarchitectonics, have triggered revolutionary progress in the field as they allow accurate detection and tracking of trace levels of major classes of drugs. This paper reviews advances in the field of biosensors for the detection of commonly abused drugs, both prescribed such as codeine and morphine, and illegal narcotics like cocaine.

show abstract

Section: Electrochemical Sensorsmentioning

confidence: 99%

Nanoarchitectonics for Abused‐Drug Biosensors

Moradi

Khalili

Septiani

et al. 2021

Small

View full text Add to dashboard Cite

show abstract

“…By incorporation of metals confined in the ordered matrix, the resulting materials (OMC-M) constitute useful structures with application as nanoprobes in electrochemical immunoassay. Fang et al [45] prepared well-dispersed uniform metallic Zn and Cd nanocrystallites incorporated to OMC and the resulting OMC-Zn (or -Cd) were conjugated with the secondary antibodies and used as signal probes in the preparation of a multiplexed immunosensor for the determination of AFP and human epidermal growth factor receptor type-2 (HER-2). A GCE modified with MWCNTs and Chit was used as the electrode platform for immobilization of the capture antibodies and further interaction with the respective antigen.…”

Section: Multiplexed Electrochemical Immunosensors Using Barcode Cmentioning

confidence: 99%

“…Furthermore, Table 2 summarizes the multiplexed immunosensors reported so far involving barcode configurations (refs. [ 6 , 12 , 13 , 14 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 ]). In the next sections we will focus not only on this type of biomarkers but also in those involved in cardiovascular diseases.…”

Section: Introductionmentioning

confidence: 99%

Multiplexed Electrochemical Immunosensors for Clinical Biomarkers

Yáñez‐Sedeño

Campuzano

Pingarrón

2017

Sensors

View full text Add to dashboard Cite

Management and prognosis of disease requires the accurate determination of specific biomarkers indicative of normal or disease-related biological processes or responses to therapy. Moreover since multiple determinations of biomarkers have demonstrated to provide more accurate information than individual determinations to assist the clinician in prognosis and diagnosis, the detection of several clinical biomarkers by using the same analytical device hold enormous potential for early detection and personalized therapy and will simplify the diagnosis providing more information in less time. In this field, electrochemical immunosensors have demonstrated to offer interesting alternatives against conventional strategies due to their simplicity, fast response, low cost, high sensitivity and compatibility with multiplexed determination, microfabrication technology and decentralized determinations, features which made them very attractive for integration in point-of-care (POC) devices. Therefore, in this review, the relevance and current challenges of multiplexed determination of clinical biomarkers are briefly introduced, and an overview of the electrochemical immunosensing platforms developed so far for this purpose is given in order to demonstrate the great potential of these methodologies. After highlighting the main features of the selected examples, the unsolved challenges and future directions in this field are also briefly discussed.

show abstract

“…Ordered mesoporous carbon (OMC) [22], a new type of carbon nanomaterial with ordered pores [23][24][25], has attracted much attention due to its regular pore structure, large pore volume, adjustable pore size and good electrical conductivity. OMCs can improve the electron transfer efficiency of electrodes and often used to construct biosensors [26,27]. With excellent thermal and electrical conductivity, good chemical corrosion resistance, OMCs are more suitable for building electrochemical sensors.…”

Section: Introductionmentioning

confidence: 99%

Electrochemical strategy with zeolitic imidazolate framework‐8 and ordered mesoporous carbon for detection of xanthine

Zhang

Jiang

Zhang

et al. 2020

IET nanobiotechnol.

View full text Add to dashboard Cite

An accurate, safe, environmentally friendly, fast and sensitive electrochemical biosensors were developed to detect xanthine in serum. The metal-organic framework ZIF-8 was synthesised and elemental gold was supported on the surface of ZIF-8 by reduction method to synthesise Ag-ZIF-8. The mesoporous carbon material and the synthesised Ag-ZIF-8 were, respectively, applied to a glassy carbon electrode to construct biosensors. The constructed biosensor has a good linear relation in the range of 1-280 μmol l −1 of xanthine and the detection limit is 0.167 μmol l −1. The relative standard deviation value in serum samples was <5%, and the recoveries were 96-106%, indicating the good selectivity, stability and reproducibility of this electrochemical biosensor.

show abstract

Metallic nanocrystallites-incorporated ordered mesoporous carbon as labels for a sensitive simultaneous multianalyte electrochemical immunoassay

Cited by 23 publications

References 51 publications

Nanoarchitectonics for Abused‐Drug Biosensors

Nanoarchitectonics for Abused‐Drug Biosensors

Multiplexed Electrochemical Immunosensors for Clinical Biomarkers

Electrochemical strategy with zeolitic imidazolate framework‐8 and ordered mesoporous carbon for detection of xanthine

Contact Info

Product

Resources

About