Metal–Organic Framework‐Derived Nickel/Cobalt‐Based Nanohybrids for Sensing Non‐Enzymatic Glucose

Wang, Lichao; Hou, Chengyi; Yu, Hao; Zhang, Qinghong; Li, Yaogang; Wang, Hongzhi

doi:10.1002/celc.202001135

Cited by 34 publications

(30 citation statements)

References 64 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Since these sugars have very similar structures, they are monosaccharides containing aldehyde or ketone groups, the COOH-GR–COOH-MWNT–AuNP nanomaterials have similar catalytic effect to these sugars ( Xu et al, 2014a ). The modified electrode can catalyze the oxidation of these sugars to form corresponding esters, which are hydrolyzed to form acids ( Wang et al, 2020 ).…”

Section: Resultsmentioning

confidence: 99%

Enzyme-Free Electrochemical Sensors for in situ Quantification of Reducing Sugars Based on Carboxylated Graphene–Carboxylated Multiwalled Carbon Nanotubes–Gold Nanoparticle–Modified Electrode

Liu

Wang

Luo³

et al. 2022

Front. Plant Sci.

View full text Add to dashboard Cite

The reducing sugars of plants, including glucose, fructose, arabinose, galactose, xylose, and mannose, are not only the energy source of plants, but also have the messenger function of hormones in signal transduction. Moreover, they also determine the quality and flavor of agricultural products. Therefore, the in situ quantification of reducing sugars in plants or agriculture products is very important in precision agriculture. However, the upper detection limit of the currently developed sugar sensor is not high enough for in situ detection. In this study, an enzyme-free electrochemical sensor for in situ detection of reducing sugars was developed. Three-dimensional composite materials based on carboxylated graphene–carboxylated multi-walled carbon nanotubes attaching with gold nanoparticles (COOH-GR–COOH-MWNT–AuNPs) were formed and applied for the non-enzymatic determination of glucose, fructose, arabinose, mannose, xylose, and galactose. It was demonstrated that the COOH-GR–COOH-MWNT–AuNP-modified electrode exhibited a good catalysis behavior to these reducing sugars due to the synergistic effect of the COOH-GR, COOH-MWNT, and AuNPs. The detection range of the sensor for glucose, fructose, arabinose, mannose, xylose, and galactose is 5–80, 2–20, 2–50, 5–60, 2–40, and 5–40 mM, respectively. To our knowledge, the upper detection limit of our enzyme-free sugar sensor is the highest compared to previous studies, which is more suitable for in situ detection of sugars in agricultural products and plants. In addition, this sensor is simple and portable, with good reproducibility and accuracy; it will have broad practical application value in precision agriculture.

show abstract

Section: Resultsmentioning

confidence: 99%

Enzyme-Free Electrochemical Sensors for in situ Quantification of Reducing Sugars Based on Carboxylated Graphene–Carboxylated Multiwalled Carbon Nanotubes–Gold Nanoparticle–Modified Electrode

Liu

Wang

Luo³

et al. 2022

Front. Plant Sci.

View full text Add to dashboard Cite

show abstract

“…Diabetes is a chronic disease that poses a significant threat to human health worldwide. It is a metabolic disease caused by insulin deficiency [186]. It causes severe long-term damage to many body organs, especially the eyes, nerves, heart, kidneys, and blood vessels [187].…”

Section: Diabetesmentioning

confidence: 99%

“…Wang et al [186] investigated metal−organic framework-derived nickel/cobalt-based nanohybrids to detect glucose in the blood. The pyrolysis of a bimetallic (Ni and Co) metal−organic framework (NiCo-MOF) was carried out at 800 • C under a nitrogen atmosphere to prepare nickel/cobalt (NiCo) alloy nanoparticles coated with graphitized carbon.…”

Section: Diabetesmentioning

confidence: 99%

Biomedical Applications of Metal−Organic Frameworks for Disease Diagnosis and Drug Delivery: A Review

2022

View full text Add to dashboard Cite

Metal−organic frameworks (MOFs) are a novel class of porous hybrid organic−inorganic materials that have attracted increasing attention over the past decade. MOFs can be used in chemical engineering, materials science, and chemistry applications. Recently, these structures have been thoroughly studied as promising platforms for biomedical applications. Due to their unique physical and chemical properties, they are regarded as promising candidates for disease diagnosis and drug delivery. Their well-defined structure, high porosity, tunable frameworks, wide range of pore shapes, ultrahigh surface area, relatively low toxicity, and easy chemical functionalization have made them the focus of extensive research. This review highlights the up-to-date progress of MOFs as potential platforms for disease diagnosis and drug delivery for a wide range of diseases such as cancer, diabetes, neurological disorders, and ocular diseases. A brief description of the synthesis methods of MOFs is first presented. Various examples of MOF-based sensors and DDSs are introduced for the different diseases. Finally, the challenges and perspectives are discussed to provide context for the future development of MOFs as efficient platforms for disease diagnosis and drug delivery systems.

show abstract

“…Recently, the Hou research group prepared nickel/cobalt (NiCo) alloy nanoparticles functionalized in graphitized carbon by pyrolyzing a bimetallic (Ni and Co) metal organic framework (NiCo-MOF) at 800 • C under a N 2 atmosphere (called as NiCo/C) (Figure 5C) [86]. The non-enzymatic glucose sensor comprising SPE/NiCo/C (SPE = screen-printed electrode) showed a high sensitivity of 265.53 µA•mM −1 •cm −2 , with an LOD of 0.2 µM (S/N = 3).…”

Section: Metal-organic-framework Derived Bimetallic Nanomaterials Based Glucose Detectionmentioning

confidence: 99%

Bimetallic Nanomaterials-Based Electrochemical Biosensor Platforms for Clinical Applications

Kannan

Maduraiveeran

2021

Micromachines

View full text Add to dashboard Cite

Diabetes is a foremost health issue that results in ~4 million deaths every year and ~170 million people suffering globally. Though there is no treatment for diabetes yet, the blood glucose level of diabetic patients should be checked closely to avoid further problems. Screening glucose in blood has become a vital requirement, and thus the fabrication of advanced and sensitive blood sugar detection methodologies for clinical analysis and individual care. Bimetallic nanoparticles (BMNPs) are nanosized structures that are of rising interest in many clinical applications. Although their fabrication shares characteristics with physicochemical methodologies for the synthesis of corresponding mono-metallic counterparts, they can display several interesting new properties and applications as a significance of the synergetic effect between their two components. These applications can be as diverse as clinical diagnostics, anti-bacterial/anti-cancer treatments or biological imaging analyses, and drug delivery. However, the exploitation of BMNPs in such fields has received a small amount of attention predominantly due to the vital lack of understanding and concerns mainly on the usage of other nanostructured materials, such as stability and bio-degradability over extended-time, ability to form clusters, chemical reactivity, and biocompatibility. In this review article, a close look at bimetallic nanomaterial based glucose biosensing approaches is discussed, concentrating on their clinical applications as detection of glucose in various real sample sources, showing substantial development of their features related to corresponding monometallic counterparts and other existing used nanomaterials for clinical applications.

show abstract

Metal–Organic Framework‐Derived Nickel/Cobalt‐Based Nanohybrids for Sensing Non‐Enzymatic Glucose

Cited by 34 publications

References 64 publications

Enzyme-Free Electrochemical Sensors for in situ Quantification of Reducing Sugars Based on Carboxylated Graphene–Carboxylated Multiwalled Carbon Nanotubes–Gold Nanoparticle–Modified Electrode

Enzyme-Free Electrochemical Sensors for in situ Quantification of Reducing Sugars Based on Carboxylated Graphene–Carboxylated Multiwalled Carbon Nanotubes–Gold Nanoparticle–Modified Electrode

Biomedical Applications of Metal−Organic Frameworks for Disease Diagnosis and Drug Delivery: A Review

Bimetallic Nanomaterials-Based Electrochemical Biosensor Platforms for Clinical Applications

Contact Info

Product

Resources

About