Metal nanoparticle ornated mesoporous silica: A potential nano-interface for uric acid detection

Venkatesvaran, Harikrishnan; Kannan, Aarthi; Mayavan, Abinaya; Dhanabal, Aishwarya; Gandhi, Sakthivel

doi:10.1016/j.micromeso.2021.111313

Cited by 14 publications

(5 citation statements)

References 49 publications

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“…However, with the development of research in this field, metal-type mediators have gradually entered researchers' field of vision. At present, the main kinds of metal type mediators are metal-organic frameworks (MOFs), metal nanomaterials, and ionic metals [148][149][150][151][152]. Using metal-type mediators in FNA biosensors can provide high sensitivity, high flexibility, and a wide detection range.…”

Section: Metal-mediated Mediatorsmentioning

confidence: 99%

“…Metal nanomaterials have certain advantages as mediators in some fields due to their excellent optical, electrical, and catalytic properties. Metal nanomaterials have been widely used in various sensors, which play an essential role in the fields of environmental detection, food safety, and nanomedicine [149][150][151]. Many of the recent studies on FNA biosensors have been focused on the use of metal nanomaterials as mediators.…”

Section: The Application Of Metal Nanomaterials In Metal Mediatorsmentioning

confidence: 99%

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Recent Advances on Functional Nucleic-Acid Biosensors

Zhang

Guo

et al. 2021

Sensors

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In the past few decades, biosensors have been gradually developed for the rapid detection and monitoring of human diseases. Recently, functional nucleic-acid (FNA) biosensors have attracted the attention of scholars due to a series of advantages such as high stability and strong specificity, as well as the significant progress they have made in terms of biomedical applications. However, there are few reports that systematically and comprehensively summarize its working principles, classification and application. In this review, we primarily introduce functional modes of biosensors that combine functional nucleic acids with different signal output modes. In addition, the mechanisms of action of several media of the FNA biosensor are introduced. Finally, the practical application and existing problems of FNA sensors are discussed, and the future development directions and application prospects of functional nucleic acid sensors are prospected.

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Section: Metal-mediated Mediatorsmentioning

confidence: 99%

Section: The Application Of Metal Nanomaterials In Metal Mediatorsmentioning

confidence: 99%

Recent Advances on Functional Nucleic-Acid Biosensors

Zhang

Guo

et al. 2021

Sensors

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“…3 However, the fluctuation of UA levels due to the lack of balance between production and excretion causes several diseases like hyperuricemia, which in turn may lead to gout disease, 4 type 2 diabetes, 5 an increase in the risk of cardiovascular diseases, 6 Lesch−Nyhan syndrome, 7 hypertension, and renal disorders. 8 Moreover, low levels of UA can be related to multiple sclerosis, Parkinson's and Alzheimer's diseases, 9 and long-term genetic disorder. Thus, there is a need to develop methods for the accurate and rapid detection of UA.…”

Section: ■ Introductionmentioning

confidence: 99%

“…The usual level of UA in the blood ranges from 0.14 to 0.4 mmol dm –3 , and in the urine, it ranges from 1.5 to 4.5 mmol dm –3 . However, the fluctuation of UA levels due to the lack of balance between production and excretion causes several diseases like hyperuricemia, which in turn may lead to gout disease, type 2 diabetes, an increase in the risk of cardiovascular diseases, Lesch–Nyhan syndrome, hypertension, and renal disorders …”

Section: Introductionmentioning

confidence: 99%

Reduced Phosphorene Quantum Dot Incorporated Flexible Bio-Electronic Device for the Detection of Uric Acid in Real Media

Sultana

Degg

Goswami

et al. 2023

ACS Appl. Electron. Mater.

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Among all developed 2D materials, phosphorene is in notable demand in recent times due to its distinctive electrical performance in biomedical applications. Zero-dimensional phosphorene quantum dot semiconducting material is a promising candidate that initiated a platform for fabricating high-performance electrical biosensors. In this study, we have successfully developed the material reduced phosphorene quantum dots (rPhQDs) of an average size of 2.1–2.3 nm using a simple hydrothermal technique. This material can be utilized as an electrical bio-sensing platform to detect uric acid in aqueous media as well as in real samples such as human blood serum and artificial urine. Biodegradable polymer composites of rPhQDs show unique current–voltage properties. They can be used to fabricate electrical devices that selectively detect uric acid in human blood serum and urine samples in the linear range of 1–5 μM. The corresponding detection limits for aqueous media, human blood serum, and artificial urine are 0.809, 0.5292, and 1.065 μM, respectively. We have investigated the driving force responsible for this selective electrical sensing and found that improvement of ionic movement in the presence of analytes plays a prominent role that can be established by measuring the transport number of the nano-bio-composite film. The device has the potential for successful detection of uric acid quantities in human blood serum and artificial urine.

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“…However, these methods are often inefficient at lower concentrations and can be expensive. Some techniques that were dynamically employed to remove food colorants are Fenton's oxidation process [30], membrane filtration, aerobic biotreatment [31], electrocoagulation [32], adsorption [33,34], and a few quantitative determination techniques such as electrochemical sensing [35,36]. Some of these methods require an additional separation system during the large-scale removal of these pollutants in discharges.…”

Section: Introductionmentioning

confidence: 99%

Photo–Redox Properties of –SO3H Functionalized Metal-Free g-C3N4 and Its Application in the Photooxidation of Sunset Yellow FCF and Photoreduction of Cr (VI)

et al. 2022

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In this work, we synthesized a metal-free sulfonic functionalized graphitic carbon nitride using sulfuric acid through the wet impregnation technique. The functionalization of sulfonic groups (–SO3H) on g-C3N4 will promote a high surface charge density and charge separation owing to its high electronegativity. The g-C3N4–SO3H shows excellent optical/electronic and surface properties towards enhanced photo–redox reactions. The sulfonic groups also facilitate the availability of more separated charge carriers for photocatalytic oxidation and reduction reactions. The as-synthesized material has been characterized by different spectroscopic tools to confirm the presence of functionalized –SO3H groups and optoelectronic possessions. The photocatalytic responses of g-C3N4–SO3H result in 99.56% photoreduction of Cr (VI) and 99.61% photooxidation of Sunset Yellow FCF within 16 min and 20 min, respectively, of visible light irradiation. The g-C3N4–SO3H catalyst exhibits a high apparent rate constant (Kapp) towards the degradation of Cr (VI), and SSY, i.e., 0.783 min−1 and 0.706 min−1, respectively. The intense optical–electrochemical properties and potentially involved active species have been analyzed through transient photocurrent, electrochemical impedance, and scavenging studies. Consequently, the photocatalytic performances are studied under different reaction parameters, and the plausible photocatalytic mechanism is discussed based on the results.

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Metal nanoparticle ornated mesoporous silica: A potential nano-interface for uric acid detection

Cited by 14 publications

References 49 publications

Recent Advances on Functional Nucleic-Acid Biosensors

Recent Advances on Functional Nucleic-Acid Biosensors

Reduced Phosphorene Quantum Dot Incorporated Flexible Bio-Electronic Device for the Detection of Uric Acid in Real Media

Photo–Redox Properties of –SO3H Functionalized Metal-Free g-C3N4 and Its Application in the Photooxidation of Sunset Yellow FCF and Photoreduction of Cr (VI)

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