Metal-free methods for the generation of benzimidazoles and 2-aminobenzimidazoles

CuO@Ag/NH2-MIL-88B(Fe) Heterojunction Photocatalyst for the Photothermal Codriven Synthesis of Benzimidazoles and Biaryls

“…Benzimidazoles, as a building block of varieties of drugs, are attractive for organic chemists to design and develop new compounds for the pharmaceutical industry. , Numerous synthetic protocols have been introduced for the synthesis of 2-substituted benzimidazole derivatives using various catalytic systems. , In addition, light-driven synthesis has been developed as an alternative and sustainable method by utilizing photocatalysts, for example, photo-organocatalysts (e.g., Rose Bengal), supported catalysts (e.g., Co-loaded TiO 2 and Ti-based coordination polymers), and bimetallic systems (e.g., PANI@Au:CuO). Recently, MOFs have been used for the deposition and/or impregnation of metal NPs on their surface and/or pores, for instance, Au/MIL-101­(Fe), Pt@MIL-101­(Fe), and PCN-222­(Pd) .…”